{"id":258,"date":"2025-05-17T18:57:15","date_gmt":"2025-05-17T09:57:15","guid":{"rendered":"https:\/\/ito-pain.com\/blog\/?p=258"},"modified":"2025-11-20T15:56:09","modified_gmt":"2025-11-20T06:56:09","slug":"post-258","status":"publish","type":"post","link":"https:\/\/ito-pain.com\/blog\/post-258\/","title":{"rendered":"\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u3068\u30c7\u30a8\u30d3\u30b4\u00ae\u30fb\u30d9\u30eb\u30bd\u30e0\u30e9\u00ae\u3001\u30de\u30a4\u30b9\u30ea\u30fc\u00ae\u306f\u3069\u3046\u9055\u3046\uff1f\u5c02\u9580\u533b\u304c\u6559\u3048\u308b\u7761\u7720\u85ac\u306e\u9078\u3073\u65b9\u3068\u4f7f\u3044\u5206\u3051"},"content":{"rendered":"\n

\u7761\u7720\u85ac\u306e\u9078\u629e\u80a2\u304c\u5897\u3048\u3066\u3044\u307e\u3059\uff5e\u81ea\u5206\u306b\u5408\u3063\u305f\u304a\u85ac\u3092\u898b\u3064\u3051\u308b\u305f\u3081\u306b<\/strong><\/h2>\n\n\n
\n
\"\"<\/figure>\n<\/div>\n\n\n

\u4e0d\u7720\u75c7\u306e\u6cbb\u7642\u3067\u4f7f\u308f\u308c\u308b\u7761\u7720\u85ac\u306b\u306f\u3001\u69d8\u3005\u306a\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u3002\u8fd1\u5e74\u3001\u65b0\u3057\u3044\u30bf\u30a4\u30d7\u306e\u7761\u7720\u85ac\u304c\u767b\u5834\u3057\u3001\u6cbb\u7642\u306e\u9078\u629e\u80a2\u304c\u5e83\u304c\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e2d\u3067\u30822024\u5e7412\u6708\u306b\u65b0\u767a\u58f2\u3055\u308c\u305f\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\uff08\u4e00\u822c\u540d\uff1a\u30c0\u30ea\u30c9\u30ec\u30ad\u30b5\u30f3\u30c8\uff09\u306f\u3001\u300c\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u300d\u3068\u3044\u3046\u30ab\u30c6\u30b4\u30ea\u306b\u5c5e\u3057\u3001\u3053\u308c\u307e\u3067\u306e\u7761\u7720\u85ac\u3068\u306f\u7570\u306a\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u7761\u7720\u3092\u6539\u5584\u3059\u308b\u304a\u85ac\u3067\u3059\u3002<\/p>\n\n\n\n

\u300c\u81ea\u5206\u306b\u306f\u3069\u306e\u7761\u7720\u85ac\u304c\u5408\u3063\u3066\u3044\u308b\u306e\u3060\u308d\u3046\uff1f\u300d\u300c\u4eca\u98f2\u3093\u3067\u3044\u308b\u85ac\u3068\u3069\u3046\u9055\u3046\u306e\uff1f\u300d\u3068\u3044\u3063\u305f\u7591\u554f\u3092\u304a\u6301\u3061\u306e\u65b9\u3082\u591a\u3044\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u3092\u3001\u540c\u3058\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u3067\u3042\u308b\u30c7\u30a8\u30d3\u30b4\u00ae\uff08\u4e00\u822c\u540d\uff1a\u30ec\u30f3\u30dc\u30ec\u30ad\u30b5\u30f3\u30c8\uff09\u3001\u30d9\u30eb\u30bd\u30e0\u30e9\u00ae\uff08\u4e00\u822c\u540d\uff1a\u30b9\u30dc\u30ec\u30ad\u30b5\u30f3\u30c8\uff09\u3001\u305d\u3057\u3066\u4ee3\u8868\u7684\u306a\u5f93\u6765\u578b\u7761\u7720\u85ac\u3067\u3042\u308b\u30de\u30a4\u30b9\u30ea\u30fc\u00ae\uff08\u4e00\u822c\u540d\uff1a\u30be\u30eb\u30d4\u30c7\u30e0\uff09\u3068\u6bd4\u8f03\u3057\u306a\u304c\u3089\u3001\u305d\u308c\u305e\u308c\u306e\u7279\u5fb4\u3001\u52b9\u679c\u3001\u526f\u4f5c\u7528\u3001\u4f7f\u3044\u5206\u3051\u306e\u30dd\u30a4\u30f3\u30c8\u306a\u3069\u3092\u5c02\u9580\u533b\u306e\u898b\u89e3\u3082\u53c2\u8003\u306b\u3057\u306a\u304c\u3089\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\n\n\n\n

\u4eca\u56de\u6bd4\u8f03\u3059\u308b\u4e3b\u306a\u7761\u7720\u85ac\u306e\u3054\u7d39\u4ecb<\/strong><\/h2>\n\n\n\n
\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\uff08\u30c0\u30ea\u30c9\u30ec\u30ad\u30b5\u30f3\u30c8\uff09<\/strong><\/td>2024\u5e74\u767a\u58f2\u3002\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u3002\u81ea\u7136\u306a\u7720\u308a\u3092\u4fc3\u3057\u3001\u4f9d\u5b58\u6027\u304c\u4f4e\u3044\u3068\u3055\u308c\u308b\u3002<\/td><\/tr>
\u30c7\u30a8\u30d3\u30b4\u00ae\uff08\u30ec\u30f3\u30dc\u30ec\u30ad\u30b5\u30f3\u30c8\uff09<\/strong><\/td>2020\u5e74\u767a\u58f2\u3002\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u3002\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u3068\u540c\u3058\u30bf\u30a4\u30d7\u3002<\/td><\/tr>
\u30d9\u30eb\u30bd\u30e0\u30e9\u00ae\uff08\u30b9\u30dc\u30ec\u30ad\u30b5\u30f3\u30c8\uff09<\/strong><\/td>2014\u5e74\u767a\u58f2\u3002\u4e16\u754c\u521d\u306e\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u3002<\/td><\/tr>
\u30de\u30a4\u30b9\u30ea\u30fc\u00ae\uff08\u30be\u30eb\u30d4\u30c7\u30e0\uff09<\/strong><\/td>\u9577\u5e74\u5e83\u304f\u4f7f\u308f\u308c\u3066\u3044\u308b\u975e\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u7cfb\u7761\u7720\u85ac\u3002\u8d85\u77ed\u6642\u9593\u578b\u3002<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
\n\n\n\n

\u3010\u5fb9\u5e95\u6bd4\u8f03\u2460\u3011\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac3\u5264\uff1a\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u30fb\u30c7\u30a8\u30d3\u30b4\u00ae\u30fb\u30d9\u30eb\u30bd\u30e0\u30e9\u00ae<\/strong><\/h2>\n\n\n\n

\u3053\u308c\u30893\u5264\u306f\u3001\u8133\u5185\u3067\u899a\u9192\u3092\u7dad\u6301\u3059\u308b\u7269\u8cea\u300c\u30aa\u30ec\u30ad\u30b7\u30f3\u300d\u306e\u50cd\u304d\u3092\u6291\u3048\u308b\u3068\u3044\u3046\u5171\u901a\u306e\u4f5c\u7528\u6a5f\u5e8f\uff08\u30c7\u30e5\u30a2\u30eb\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff1aDORA\uff09\u3092\u6301\u3061\u307e\u3059\u304c\u3001\u305d\u308c\u305e\u308c\u306b\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u7279\u5fb4\u9805\u76ee<\/strong><\/td>\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae (\u30c0\u30ea\u30c9\u30ec\u30ad\u30b5\u30f3\u30c8)<\/strong><\/td>\u30c7\u30a8\u30d3\u30b4\u00ae (\u30ec\u30f3\u30dc\u30ec\u30ad\u30b5\u30f3\u30c8)<\/strong><\/td>\u30d9\u30eb\u30bd\u30e0\u30e9\u00ae (\u30b9\u30dc\u30ec\u30ad\u30b5\u30f3\u30c8)<\/strong><\/td><\/tr>
\u767a\u58f2\u5e74\uff08\u56fd\u5185\uff09<\/strong><\/td>2024\u5e74<\/td>2020\u5e74<\/td>2014\u5e74<\/td><\/tr>
\u88fd\u9020\u4f1a\u793e<\/strong><\/td>\u30a4\u30c9\u30eb\u30b7\u30a2<\/td>\u30a8\u30fc\u30b6\u30a4<\/td>MSD<\/td><\/tr>
\u534a\u6e1b\u671f\uff08\u52b9\u679c\u6301\u7d9a\u76ee\u5b89\uff09<\/strong><\/td>\u7d046.6\u6642\u9593\uff08\u77ed\u3044\uff09<\/td>\u7d0447.4\u6642\u9593\uff08\u975e\u5e38\u306b\u9577\u3044\uff09<\/td>\u7d0410\u6642\u9593\uff08\u4e2d\u9593\uff09<\/td><\/tr>
\u6700\u9ad8\u8840\u4e2d\u6fc3\u5ea6\u5230\u9054\u6642\u9593<\/strong><\/td>\u7d041.0\u6642\u9593<\/td>\u7d041.5\u6642\u9593<\/td>\u7d041.5\u6642\u9593<\/td><\/tr>
\u5165\u7720\u52b9\u679c\uff08\u5c02\u9580\u533b\u5370\u8c61\uff09<\/strong><\/td>\u30c7\u30a8\u30d3\u30b4\u00ae\u3068\u540c\u7a0b\u5ea6<\/td>\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u3068\u540c\u7a0b\u5ea6<\/td>\u3084\u3084\u52a3\u308b<\/td><\/tr>
\u6301\u3061\u8d8a\u3057\u52b9\u679c\uff08\u7fcc\u671d\u306e\u7720\u6c17\uff09<\/strong><\/td>\u6700\u3082\u5c11\u306a\u3044\u3068\u3055\u308c\u308b<\/td>\u6b8b\u308a\u3084\u3059\u3044\u50be\u5411\u3042\u308a<\/td>\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u3088\u308a\u306f\u6b8b\u308a\u3084\u3059\u3044<\/td><\/tr>
\u60aa\u5922\u306e\u526f\u4f5c\u7528\u5831\u544a<\/strong><\/td>\u4ed62\u5264\u3088\u308a\u5c11\u306a\u3044\u3068\u306e\u30c7\u30fc\u30bf\u30fb\u898b\u89e3\u3042\u308a<\/td>\u5831\u544a\u3042\u308a<\/td>\u5831\u544a\u3042\u308a<\/td><\/tr>
\u5264\u5f62(mg)<\/strong><\/td>25, 50 (\u304a\u306b\u304e\u308a\u578b\u3001\u5206\u5272\u3057\u306b\u304f\u3044)<\/td>2.5, 5, 10 (\u5206\u5272\u53ef\u3001\u7528\u91cf\u8abf\u7bc0\u3057\u3084\u3059\u3044)<\/td>10, 15 (\u5206\u5272\u4e0d\u53ef)<\/td><\/tr>
\u9ad8\u9f62\u8005\u7528\u91cf<\/strong><\/td>25mg<\/td>5mg\uff5e10mg (\u6700\u5927)<\/td>10mg<\/td><\/tr>
CYP3A<\/strong>\u963b\u5bb3\u85ac\u4f75\u7528\u6642<\/strong><\/td>25mg<\/td>2.5mg<\/td>10mg<\/td><\/tr>
\u7981\u5fcc\uff08\u4e3b\u306a\u3082\u306e\uff09<\/strong><\/td>CYP3A\u5f37\u963b\u5bb3\u85ac\u4f75\u7528\u3001\u91cd\u5ea6\u809d\u6a5f\u80fd\u969c\u5bb3<\/td>\u91cd\u5ea6\u809d\u6a5f\u80fd\u969c\u5bb3<\/td>CYP3A\u5f37\u963b\u5bb3\u85ac\u4f75\u7528<\/td><\/tr>
\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u89aa\u548c\u6027<\/strong><\/td>OX1R > OX2R (OX1R\u3078\u306e\u4f5c\u7528\u304c\u5f37\u3044)<\/td>OX1R << OX2R (OX2R\u3078\u306e\u4f5c\u7528\u304c\u975e\u5e38\u306b\u5f37\u3044)<\/td>OX1R \u2266 OX2R<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
\n\n\n\n

\u5c02\u9580\u533b\u306b\u3088\u308b\u4f7f\u3044\u5206\u3051\u306e\u30dd\u30a4\u30f3\u30c8\uff08\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac3\u5264\uff09<\/strong><\/h2>\n\n\n
\n
\"\"<\/figure>\n<\/div>\n\n\n
    \n
  • \u7fcc\u671d\u306e\u7720\u6c17\u3084\u6301\u3061\u8d8a\u3057\u3092\u7279\u306b\u907f\u3051\u305f\u3044\u65b9\uff1a<\/strong> \u534a\u6e1b\u671f\u304c\u6700\u3082\u77ed\u3044\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae<\/strong>\u304c\u7b2c\u4e00\u9078\u629e\u80a2\u3068\u306a\u308b\u3068\u8003\u3048\u307e\u3059\u3002<\/li>\n\n\n\n
  • \u4e2d\u9014\u899a\u9192\u3084\u65e9\u671d\u899a\u9192\u304c\u7279\u306b\u5f37\u3044\u65b9\u3001\u52b9\u679c\u306e\u6301\u7d9a\u3092\u91cd\u8996\u3059\u308b\u65b9\uff1a<\/strong> \u534a\u6e1b\u671f\u304c\u975e\u5e38\u306b\u9577\u3044\u30c7\u30a8\u30d3\u30b4\u00ae<\/strong>\u304c\u9069\u3057\u3066\u3044\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u7fcc\u671d\u3078\u306e\u5f71\u97ff\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n\n\n\n
  • \u5165\u7720\u56f0\u96e3\u306b\u3082\u5bfe\u5fdc\u3057\u3064\u3064\u3001\u3042\u308b\u7a0b\u5ea6\u306e\u6301\u7d9a\u3082\u6b32\u3057\u3044\u65b9\uff1a<\/strong> \u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae<\/strong>\u3084\u30c7\u30a8\u30d3\u30b4\u00ae<\/strong>\u304c\u691c\u8a0e\u3055\u308c\u307e\u3059\u3002\u30d9\u30eb\u30bd\u30e0\u30e9\u00ae\u306f\u5165\u7720\u52b9\u679c\u304c\u3084\u3084\u30de\u30a4\u30eb\u30c9\u3068\u306e\u8a55\u4fa1\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n
  • \u7d30\u3084\u304b\u306a\u7528\u91cf\u8abf\u7bc0\u304c\u5fc5\u8981\u306a\u65b9\u3001\u526f\u4f5c\u7528\u3092\u898b\u306a\u304c\u3089\u614e\u91cd\u306b\u5897\u91cf\u3057\u305f\u3044\u65b9\uff1a<\/strong> 3\u6bb5\u968e\u306e\u7528\u91cf\u304c\u3042\u308a\u5206\u5272\u3082\u53ef\u80fd\u306a\u30c7\u30a8\u30d3\u30b4\u00ae<\/strong>\u304c\u4f7f\u3044\u3084\u3059\u3044\u3067\u3059\u3002<\/li>\n\n\n\n
  • \u60aa\u5922\u304c\u5fc3\u914d\u306a\u65b9\uff1a<\/strong> \u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae<\/strong>\u306f\u4ed6\u306e2\u5264\u3068\u6bd4\u8f03\u3057\u3066\u60aa\u5922\u306e\u5831\u544a\u304c\u5c11\u306a\u3044\u3068\u3044\u3046\u30c7\u30fc\u30bf\u3084\u5c02\u9580\u5bb6\u306e\u610f\u898b\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n
    \n\n\n\n

    \u3010\u5fb9\u5e95\u6bd4\u8f03\u2461\u3011\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae \u3068 \u4ee3\u8868\u7684\u306a\u5f93\u6765\u578b\u7761\u7720\u85ac\u30de\u30a4\u30b9\u30ea\u30fc\u00ae\u306e\u6bd4\u8f03<\/strong><\/h2>\n\n\n\n

    \u6b21\u306b\u3001\u65b0\u3057\u3044\u30bf\u30a4\u30d7\u306e\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u3068\u3001\u9577\u5e74\u5e83\u304f\u4f7f\u308f\u308c\u3066\u3044\u308b\u30de\u30a4\u30b9\u30ea\u30fc\u00ae\uff08\u975e\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u7cfb\uff09\u3092\u6bd4\u8f03\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u4f5c\u7528\u306e\u4ed5\u65b9\u304c\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

    \u7279\u5fb4\u9805\u76ee<\/strong><\/td>\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae (\u30c0\u30ea\u30c9\u30ec\u30ad\u30b5\u30f3\u30c8)<\/strong><\/td>\u30de\u30a4\u30b9\u30ea\u30fc\u00ae (\u30be\u30eb\u30d4\u30c7\u30e0)<\/strong><\/td><\/tr>
    \u4f5c\u7528\u6a5f\u5e8f<\/strong><\/td>\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\uff08\u899a\u9192\u3092\u6291\u3048\u308b\uff09<\/td>GABA\u53d7\u5bb9\u4f53\u4f5c\u52d5\uff08\u8133\u306e\u6d3b\u52d5\u3092\u93ae\u9759\uff09<\/td><\/tr>
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    \u4f9d\u5b58\u6027\u30fb\u96e2\u8131\u75c7\u72b6\u30ea\u30b9\u30af<\/strong><\/td>\u6975\u3081\u3066\u4f4e\u3044\u3068\u3055\u308c\u308b<\/td>\u9577\u671f\u4f7f\u7528\u3067\u8d77\u3053\u308a\u3046\u308b\u3002<\/td><\/tr>
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    \u526f\u4f5c\u7528\uff08\u305d\u306e\u4ed6\uff09<\/strong><\/td>\u60aa\u5922\u3001\u5e7b\u899a\uff08\u30ec\u30e0\u7761\u7720\u95a2\u9023\uff09\u306e\u53ef\u80fd\u6027<\/td>\u7761\u7720\u968f\u4f34\u75c7\u72b6\uff08\u5922\u904a\u75c5\u306a\u3069\uff09\u3001\u3075\u3089\u3064\u304d\u306e\u53ef\u80fd\u6027<\/td><\/tr>
    \u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1<\/strong><\/td>\u306a\u3057\uff082025\u5e745\u6708\u73fe\u5728\uff09<\/td>\u3042\u308a\uff08\u85ac\u4fa1\u304c\u5b89\u3044\uff09<\/td><\/tr>
    \u85ac\u4fa1\uff08\u5148\u767a\u54c1\u76ee\u5b89\uff09<\/strong><\/td>25mg:\u7d0457\u5186, 50mg:\u7d0491\u5186<\/td>5mg:\u7d0418\u5186, 10mg:\u7d0427\u5186<\/td><\/tr>
    \u7981\u5fcc\uff08\u4e3b\u306a\u3082\u306e\uff09<\/strong><\/td>CYP3A\u5f37\u963b\u5bb3\u85ac\u4f75\u7528\u3001\u91cd\u5ea6\u809d\u6a5f\u80fd\u969c\u5bb3<\/td>\u6025\u6027\u9589\u585e\u9685\u89d2\u7dd1\u5185\u969c\u3001\u91cd\u75c7\u7b4b\u7121\u529b\u75c7<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
    \n\n\n\n

    \u5c02\u9580\u533b\u306b\u3088\u308b\u4f7f\u3044\u5206\u3051\u306e\u30dd\u30a4\u30f3\u30c8\uff08\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae vs \u30de\u30a4\u30b9\u30ea\u30fc\u00ae\uff09<\/strong><\/h2>\n\n\n
    \n
    \"\"<\/figure>\n<\/div>\n\n\n
      \n
    • \u4f9d\u5b58\u6027\u3084\u9577\u671f\u4f7f\u7528\u3092\u61f8\u5ff5\u3059\u308b\u65b9\u3001\u81ea\u7136\u306a\u7720\u308a\u3092\u6c42\u3081\u308b\u65b9\uff1a<\/strong> \u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae<\/strong>\uff08\u307e\u305f\u306f\u4ed6\u306e\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff09\u304c\u9069\u3057\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n
    • \u4e2d\u9014\u899a\u9192\u3084\u65e9\u671d\u899a\u9192\u306b\u3082\u3057\u3063\u304b\u308a\u5bfe\u5fdc\u3057\u305f\u3044\u65b9\uff1a<\/strong> \u4f5c\u7528\u6642\u9593\u306e\u9577\u3044\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae<\/strong>\u304c\u30de\u30a4\u30b9\u30ea\u30fc\u00ae\u3088\u308a\u9069\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\uff08Di Marco et al.\u306e\u7814\u7a76\u3067\u306f\u3001\u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u306f\u591c\u9593\u899a\u9192\u3092\u6e1b\u3089\u3057\u518d\u5165\u7720\u3092\u52a9\u3051\u308b\u52b9\u679c\u304c\u793a\u5506\uff09<\/li>\n\n\n\n
    • \u5bdd\u3064\u304d\u306e\u60aa\u3055\u304c\u4e3b\u3067\u3001\u5373\u52b9\u6027\u3092\u6c42\u3081\u308b\u65b9\u3001\u5c6f\u7528\uff08\u5fc5\u8981\u306a\u6642\u3060\u3051\u4f7f\u3046\uff09\u3092\u5e0c\u671b\u3059\u308b\u65b9\uff1a<\/strong> \u30de\u30a4\u30b9\u30ea\u30fc\u00ae<\/strong>\u304c\u9078\u629e\u80a2\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u4f9d\u5b58\u6027\u3084\u5065\u5fd8\u306e\u30ea\u30b9\u30af\u3001\u4f5c\u7528\u6642\u9593\u306e\u77ed\u3055\uff08\u4e2d\u9014\u899a\u9192\u306b\u306f\u4e0d\u5411\u304d\u306a\u5834\u5408\u304c\u3042\u308b\uff09\u3092\u7406\u89e3\u3057\u3066\u304a\u304f\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n
    • \u88dc\u8db3<\/strong><\/li>\n<\/ul>\n\n\n\n

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      \n\n\n\n

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      \n
      \"\"<\/figure>\n<\/div>\n\n\n

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        \n
      • \u85ac\u7269\u76f8\u4e92\u4f5c\u7528\uff1a<\/strong> \u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u306f\u7279\u5b9a\u306e\u85ac\u5264\uff08CYP3A\u3092\u5f37\u304f\u963b\u5bb3\u3059\u308b\u4e00\u90e8\u306e\u6297\u751f\u5264\uff09\u3068\u306e\u4f75\u7528\u304c\u7981\u5fcc\u3067\u3059\u3002\u30c7\u30a8\u30d3\u30b4\u00ae\u3084\u30d9\u30eb\u30bd\u30e0\u30e9\u00ae\u3082\u540c\u69d8\u306b\u6ce8\u610f\u3059\u308b\u85ac\u7269\u304c\u3042\u308a\u307e\u3059\u3002\u30de\u30a4\u30b9\u30ea\u30fc\u00ae\u3082\u4ed6\u306e\u85ac\u5264\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306e\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u670d\u7528\u4e2d\u306e\u85ac\u306f\u5fc5\u305a\u5168\u3066\u533b\u5e2b\u306b\u4f1d\u3048\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n\n\n\n
      • \u4f75\u7528\u306b\u3064\u3044\u3066\uff1a<\/strong>\n
          \n
        • \u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u3001\u30c7\u30a8\u30d3\u30b4\u00ae\u3001\u30d9\u30eb\u30bd\u30e0\u30e9\u00ae\u3068\u3044\u3063\u305f\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u540c\u58eb\u306e\u4f75\u7528\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/li>\n\n\n\n
        • \u30af\u30fc\u30d3\u30d3\u30c3\u30af\u00ae\u3068\u30de\u30a4\u30b9\u30ea\u30fc\u00ae\u306e\u3088\u3046\u306a\u4f5c\u7528\u6a5f\u5e8f\u306e\u7570\u306a\u308b\u7761\u7720\u85ac\u306e\u4f75\u7528\u3082\u3001\u904e\u5ea6\u306e\u93ae\u9759\u4f5c\u7528\u304c\u51fa\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u539f\u5247\u3068\u3057\u3066\u884c\u308f\u308c\u307e\u305b\u3093\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n
        • \u60a3\u8005\u3055\u3093\u306e\u72b6\u614b\u306b\u3088\u308b\u6ce8\u610f\uff1a<\/strong> \u809d\u6a5f\u80fd\u969c\u5bb3\u3084\u814e\u6a5f\u80fd\u969c\u5bb3\u306e\u3042\u308b\u65b9\u3001\u9ad8\u9f62\u8005\u306e\u65b9\u3001\u598a\u5a20\u4e2d\u30fb\u6388\u4e73\u4e2d\u306e\u65b9\u306a\u3069\u306f\u3001\u85ac\u5264\u306e\u9078\u629e\u3084\u7528\u91cf\u8abf\u6574\u306b\u7279\u5225\u306a\u914d\u616e\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n
          \n\n\n\n

          \u6700\u9069\u306a\u7761\u7720\u85ac\u306f\u4e00\u4eba\u3072\u3068\u308a\u9055\u3044\u307e\u3059 \uff5e\u5fc5\u305a\u533b\u5e2b\u306b\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046<\/strong><\/strong><\/h2>\n\n\n\n

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