{"id":1142,"date":"2026-05-17T21:00:47","date_gmt":"2026-05-17T12:00:47","guid":{"rendered":"https:\/\/ito-pain.com\/blog\/?p=1142"},"modified":"2026-05-17T21:00:48","modified_gmt":"2026-05-17T12:00:48","slug":"post-1142","status":"publish","type":"post","link":"https:\/\/ito-pain.com\/blog\/post-1142\/","title":{"rendered":"\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\uff08nociplastic pain\uff09\u3068\u306f"},"content":{"rendered":"\n<p>\u6162\u6027\u75bc\u75db\u306b\u304a\u3044\u3066\u306f\u3001\u3057\u3070\u3057\u3070\u75bc\u75db\u306e\u539f\u56e0\u3068\u306a\u308b\u4fb5\u8972\u304c\u53d6\u308a\u9664\u304b\u308c\u305f\u5f8c\u3084\u7d44\u7e54\u7684\u306b\u306f\u4fee\u5fa9\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u898b\u3048\u308b\u5834\u5408\u3001\u3082\u3057\u304f\u306f\u4fb5\u8972\u304c\u5168\u304f\u306a\u3044\u72b6\u614b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u75db\u307f\u304c\u767a\u751f\u3057\u7d99\u7d9a\u3059\u308b\u6cbb\u7642\u306b\u96e3\u6e0b\u3059\u308b\u75db\u307f\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u767a\u751f\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u306f\u3063\u304d\u308a\u5206\u304b\u3063\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u3053\u306e\u3088\u3046\u306a\u96e3\u6cbb\u6027\u306e\u75bc\u75db\u306b\u5bfe\u3057\u3066\u30012016\u5e74\u3001\u56fd\u969b\u75bc\u75db\u5b66\u4f1a\uff08IASP\uff1aInternational Association for the Study of Pain\uff1b\u75db\u307f\u306b\u95a2\u3057\u3066\u6a29\u5a01\u306e\u3042\u308b\u5b66\u4f1a\uff09\u306b\u3088\u3063\u3066\u3001nociceptive pain\uff08\u4fb5\u5bb3\u53d7\u5bb9\u6027\u75bc\u75db\uff09\u3068neuropathic pain\uff08\u795e\u7d4c\u56e0\u6027\u75bc\u75db\uff09\u3068\u306f\u7570\u306a\u308b\u75bc\u75db\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u8aac\u660e\u3059\u308b\u305f\u3081\u306b\u3001\u7b2c\u4e09\u306e\u75db\u307f\u3068\u3057\u3066nociplastic pain\u3068\u3044\u3046\u6982\u5ff5\u304c\u63d0\u5531\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>Nociplastic pain\u306f\u30012021 \u5e74\u306b\u65e5\u672c\u75db\u307f\u95a2\u9023\u5b66\u4f1a\u9023\u5408\u304b\u3089\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u3068\u8a33\u3055\u308c\u767a\u8868\u3055\u308c\u307e\u3057\u305f\uff08\u4ee5\u964d\u3001\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u3068\u793a\u3059\uff09\u3002<\/p>\n\n\n\n<p>\u75db\u307f\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3088\u308b\u5206\u985e\uff1a\u73fe\u5728\u5927\u304d\u304f\uff13\u3064\u306b\u5206\u985e\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30fb\u4fb5\u5bb3\u53d7\u5bb9\u6027\u75bc\u75db\uff08nociceptive pain\uff09\uff1a\u8eab\u4f53\u306e\u3069\u3053\u304b\u306e\u7d44\u7e54\u304c\u50b7\u3064\u3044\u305f\u308a\u3001\u50b7\u3064\u304d\u305d\u3046\u306b\u306a\u3063\u305f\u3068\u304d\u306b\u3001\u305d\u306e\u5371\u967a\u3092\u77e5\u3089\u305b\u308b\u305f\u3081\u306b\u8d77\u3053\u308b\u75db\u307f\u3067\u3059\u3002<br>\u30fb\u795e\u7d4c\u969c\u5bb3\u6027\u75bc\u75db\uff08neuropathic pain\uff09\uff1a\u4f53\u6027\u611f\u899a\u795e\u7d4c\u7cfb\u306f\u3001\u76ae\u819a\u30fb\u7b4b\u30fb\u95a2\u7bc0\u306a\u3069\u304b\u3089\u306e\u611f\u899a\u60c5\u5831\uff08\u89e6\u899a\u30fb\u6e29\u5ea6\u30fb\u75db\u307f\u30fb\u4f4d\u7f6e\u611f\u899a\u306a\u3069\uff09\u3092\u672b\u68a2\u304b\u3089\u4e2d\u67a2\u795e\u7d4c\u3078\u4f1d\u3048\u3001\u3055\u3089\u306b\u9aa8\u683c\u7b4b\u306e\u968f\u610f\u904b\u52d5\u3092\u5236\u5fa1\u3059\u308b\u611f\u899a\u3092\u62c5\u3046\u795e\u7d4c\u7cfb\u3067\u3059\u304c\u3001\u3053\u306e\u4f53\u6027\u611f\u899a\u795e\u7d4c\u7cfb\u306e\u969c\u5bb3\u306b\u8d77\u56e0\u3059\u308b\u75db\u307f\u3067\u3059\u3002<br>\u30fb\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\uff08nociplastic pain\uff09\uff1a<strong>\u4e2d\u67a2\u795e\u7d4c\u7cfb\uff08\u8133\uff09\u306e\u75db\u307f\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u5909\u5316<\/strong>\u306b\u3088\u3063\u3066\u751f\u3058\u308b\u75db\u307f\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4eca\u56de\u306f\u3001\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u306b\u3064\u3044\u3066\u306e\u8a71\u3068\u306a\u308a\u307e\u3059\u3002\u53c2\u8003\u6587\u732e\u306f\u3001\u4e0b\u8a18\u306e\u8ad6\u6587\u3067\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>Nat Rev Neurol. 2024 Jun;20(6):347-363. doi: 10.1038\/s41582-024-00966-8. Epub 2024 May 16.<br>Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms<br>Chelsea M Kaplan, Eoin Kelleher, Anushka Irani, Andrew Schrepf, Daniel J Clauw , Steven E Harte<\/p>\n<\/blockquote>\n\n\n\n<p>\u672c\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u3092\u6709\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u30d2\u30c8\u88ab\u9a13\u8005\u304b\u3089\u306e\u7814\u7a76\u7d50\u679c\u3092\u691c\u8a3c\u3057\u3001\u7279\u306b\u6162\u6027\u91cd\u8907\u75bc\u75db\u72b6\u614b\u60a3\u8005\uff08COPC\uff1aChronic Overlapping Pain Conditions\uff09\u306e\u81e8\u5e8a\u7814\u7a76\u306b\u7126\u70b9\u304c\u3042\u3066\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u3068\u306f\u3001\u3069\u306e\u3088\u3046\u306a\u75be\u60a3\u306b\u8a8d\u3081\u3089\u308c\u308b\u306e\u304b<\/h2>\n\n\n\n<p>\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u304c\u4e3b\u8981\u306a\u75bc\u75db\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u75be\u60a3\u3068\u3057\u3066\u3001\u7dda\u7dad\u7b4b\u75db\u75c7\uff08FM\uff09\u30fb\u9593\u8cea\u6027\u8180\u80f1\u708e\uff0f\u8180\u80f1\u75db\u75c7\u5019\u7fa4\uff08IC\/BPS\uff09\u30fb\u904e\u654f\u6027\u8178\u75c7\u5019\u7fa4\uff08IBS\uff09\u30fb\u6162\u6027\u8170\u75db\uff08cLBP\uff09\u30fb\u6162\u6027\u306e\u7dca\u5f35\u578b\u982d\u75db\u304a\u3088\u3073\u7247\u982d\u75db\u30fb\u984e\u95a2\u7bc0\u75c7\uff08TMD\uff09\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002<br>\u3053\u308c\u3089\u306e\u75be\u60a3\u306f\u3001\u6700\u8fd1\u3067\u306f\u6162\u6027\u91cd\u8907\u75bc\u75db\u72b6\u614b\uff08\u4ee5\u964dCOPCs\u3068\u7565\u3059\uff09\u3068\u7dcf\u79f0\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\u3053\u308c\u4ee5\u5916\u306b\u3082\u3042\u3089\u3086\u308b\u6162\u6027\u75bc\u75db\u75be\u60a3\u306b\u304a\u3044\u3066\u3001\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u304c\u767a\u73fe\u3059\u308b\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u75db\u307f\u4ee5\u5916\u306e\u75c7\u72b6\u3068\u3057\u3066<\/h2>\n\n\n\n<p>\u5026\u6020\u611f\u3001\u7761\u7720\u304b\u3089\u306e\u56de\u5fa9\u4e0d\u826f\u3001\u6291\u3046\u3064\u6c17\u5206\u3001\u96c6\u4e2d\u529b\u3084\u77ed\u671f\u8a18\u61b6\u306e\u969c\u5bb3\u3001\u8996\u899a\u3001\u8074\u899a\u3001\u89e6\u899a\u523a\u6fc0\u306b\u5bfe\u3059\u308b\u904e\u654f\u75c7\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\uff08\u4e0b\u56f3\uff09\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"617\" height=\"600\" src=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-10-617x600.png\" alt=\"\" class=\"wp-image-1143\" srcset=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-10-617x600.png 617w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-10-309x300.png 309w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-10.png 648w\" sizes=\"auto, (max-width: 617px) 100vw, 617px\" \/><\/figure>\n<\/div>\n\n\n<p>2019\u5e74\u7248\u56fd\u969b\u75be\u75c5\u5206\u985e\uff08ICD-11\uff09\u3067\u306f\u3001COPCs\u75be\u60a3\u306f\u300c\u6162\u6027\u4e00\u6b21\u6027\u75bc\u75db\u300d\u3068\u5206\u985e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u6162\u6027\u75bc\u75db\u306e\u539f\u56e0\u304c\u660e\u3089\u304b\u306a\u6162\u6027\u4e8c\u6b21\u6027\u75bc\u75db\u306e\u539f\u56e0\u3067\u306f\u8aac\u660e\u3067\u304d\u306a\u3044\u5834\u5408\u306b\u8a3a\u65ad\u3055\u308c\u307e\u3059\u3002\uff08\u6162\u6027\u75bc\u75db\u3068\u306f\u30013\u304b\u6708\u4ee5\u4e0a\u306e\u6301\u7d9a\u307e\u305f\u306f\u518d\u767a\u3059\u308b\u75bc\u75db\u306e\u3053\u3068\u3092\u8a00\u3044\u307e\u3059\u3002\uff09<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6709\u75c5\u7387<\/h3>\n\n\n\n<p>\u69d8\u3005\u306aCOPCs\u306e\u6709\u75c5\u7387\u306f\u3001\u7dda\u7dad\u7b4b\u75db\u75c7\uff08FM\uff09\u3084\u9593\u8cea\u6027\u8180\u80f1\u708e\/\u8180\u80f1\u75db\u75c7\u5019\u7fa4\uff08IC\/BPS\uff09\u306a\u3069\u306e\u75be\u60a3\u3067\u306f2\uff5e6%\u3001\u6162\u6027\u8170\u75db\uff08cLBP\uff09\u3001\u984e\u95a2\u7bc0\u75c7\uff08TMD\uff09\u3001\u904e\u654f\u6027\u8178\u75c7\u5019\u7fa4\uff08IBS\uff09\u3067\u306f\u305d\u308c\u305e\u308c\u7d0410%\u3068\u5e45\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6570\u5024\u306f\u3001\u4e00\u822c\u4eba\u53e3\u306e\u5c11\u306a\u304f\u3068\u30828\uff5e11%\u304cCOPCs\u3092\u62b1\u3048\u3066\u3044\u308b\u3068\u3044\u3046\u63a8\u5b9a\u5024\u3068\u4e00\u81f4\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u306e\u4e3b\u8981\u306a\u75c7\u72b6<\/h3>\n\n\n\n<p>\u30fb\u5b58\u5728\u3059\u308b\u672b\u68a2\u75c5\u5909\u306b\u4e0d\u91e3\u308a\u5408\u3044\u306a\u307b\u3069\u306e\u5f37\u3044\u75db\u307f<br>\u30fb\u75db\u307f\u304c\u3001\u3057\u3070\u3057\u3070\u6301\u7d9a\u7684\u3067\u3001\u5168\u8eab\u306b\u5e83\u7bc4\u56f2\u306b\u5e83\u304c\u308b\u50be\u5411<br>\u30fb\u75db\u307f\u306e\u90e8\u4f4d\u304c\u7279\u5b9a\u3057\u306b\u304f\u3044\u5834\u5408\u3001\u89e3\u5256\u5b66\u7684\u5206\u5e03\u3068\u306f\u7570\u306a\u308b\u5834\u5408<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u75db\u307f\u306e\u6027\u8cea<\/h3>\n\n\n\n<p>\u30fb\u4e00\u822c\u7684\u306b\u920d\u304f\u3001\u6df1\u304f\u3001\u3046\u305a\u304f\u3088\u3046\u306a\u75db\u307f<br>\u30fb\u6642\u9593\u3068\u3068\u3082\u306b\u90e8\u4f4d\u3068\u5f37\u5ea6\u304c\u5909\u5316<br>\u30fb\u60aa\u5316\u3057\u305f\u308a\u8efd\u6e1b\u3057\u305f\u308a\u3059\u308b\u3053\u3068\u304c\u3088\u304f\u3042\u308b<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u306e\u767a\u75c7\u306b\u95a2\u4e0e\u3059\u308b\u5371\u967a\u56e0\u5b50<\/h2>\n\n\n\n<p>2016\u5e74\u306b\u521d\u3081\u3066\u63d0\u5531\u3055\u308c\u305f\u305f\u3081\u3001\u5371\u967a\u56e0\u5b50\u306e\u307f\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u7814\u7a76\u306f\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u6162\u6027\u91cd\u8907\u75bc\u75db\u72b6\u614b\uff08COPCs\uff09\u3001\u7279\u306b\u7dda\u7dad\u7b4b\u75db\u75c7\u306b\u95a2\u3059\u308b\u7814\u7a76\u306f\u3001\u5171\u901a\u306e\u5371\u967a\u56e0\u5b50\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u624b\u304c\u304b\u308a\u3068\u306a\u308a\u307e\u3059\u3002\u4e0b\u56f3\u306b\u793a\u3059\u56e0\u5b50\u304c\u3001\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u306e\u767a\u75c7\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"431\" src=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-13-800x431.png\" alt=\"\" class=\"wp-image-1146\" srcset=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-13-800x431.png 800w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-13-400x215.png 400w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-13.png 819w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p>\u3057\u304b\u3057\u3001\u4e0a\u8a18\u306e\u66dd\u9732\u3092\u53d7\u3051\u305f\u591a\u304f\u306e\u4eba\u306f\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u3092\u767a\u75c7\u305b\u305a\u3001\u3053\u306e\u75bc\u75db\u306e\u767a\u75c7\u3092\u4fc3\u9032\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u6291\u5236\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u4f9d\u7136\u3068\u3057\u3066\u4e0d\u660e\u3067\u3059\u3002<\/p>\n\n\n\n<h3 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class=\"wp-block-heading\">\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30fb\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u5909\u5316\u30fb\u514d\u75ab\u30e1\u30ab\u30cb\u30ba\u30e0\u30fb\u672b\u68a2\u7d44\u7e54\u306e\u8abf\u7bc0\u306e\u7570\u5e38<\/strong><\/h3>\n\n\n\n<p>\u53c2\u8003\u6587\u732e\u3088\u308a\u4e0b\u56f3\u3092\u629c\u7c8b\u3057\u8ee2\u8a18\uff08\u4e00\u90e8\u5909\u66f4\uff09\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"481\" src=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-12-800x481.png\" alt=\"\" class=\"wp-image-1145\" srcset=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-12-800x481.png 800w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-12-400x241.png 400w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-12.png 886w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<h3 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class=\"wp-block-heading\">\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u306e2\u3064\u306e\u6f5c\u5728\u7684\u306a\u30b5\u30d6\u30bf\u30a4\u30d7 \uff1a<\/h2>\n\n\n\n<p>\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u306f\u3001\u75db\u307f\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u8aac\u660e\u3059\u308b\u65b0\u3057\u3044\u6982\u5ff5\u3067\u3001\u5927\u304d\u304f\u4ee5\u4e0b\u306b\u8ff0\u3079\u308b\uff12\u3064\u306e\u75db\u307f\u306e\u7d4c\u8def\uff08\u30c8\u30c3\u30d7\u30c0\u30a6\u30f3\u578b\u3068\u30dc\u30c8\u30e0\u30a2\u30c3\u30d7\u578b\uff09\uff08\u4e0b\u56f3\uff09\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"704\" height=\"600\" src=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-14-704x600.png\" alt=\"\" class=\"wp-image-1147\" srcset=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-14-704x600.png 704w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-14-352x300.png 352w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-14.png 791w\" sizes=\"auto, (max-width: 704px) 100vw, 704px\" \/><\/figure>\n<\/div>\n\n\n<p>\u75c5\u614b\u751f\u7406\u3068\u3057\u3066\u3001\u4e0a\u884c\u6027\u75bc\u75db\u60c5\u5831\u306e\u5897\u5e45\u304a\u3088\u3073\uff0f\u307e\u305f\u306f\u4e0b\u884c\u6027\u6291\u5236\u6027\u75bc\u75db\u5236\u5fa1\u306e\u55aa\u5931\u304c\u542b\u307e\u308c\u3001\u3053\u308c\u3089\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u810a\u9ac4\u3001\u8133\u5e79\u3001\u76ae\u8cea\u4e0b\u69cb\u9020\u3001\u304a\u3088\u3073\u65b0\u76ae\u8cea\u306e\u30ec\u30d9\u30eb\u3067\u8d77\u3053\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u30dc\u30c8\u30e0\u30a2\u30c3\u30d7\u578b\u306f\u3001\u672b\u68a2\u306e\u75db\u307f\u30fb\u708e\u75c7\u30fb\u7d44\u7e54\u640d\u50b7\u306a\u3069\u304c\u9577\u671f\u3084\u53cd\u5fa9\u7684\u306b\u523a\u6fc0\u3068\u3057\u3066\u52a0\u3048\u3089\u308c\u3001\u305d\u308c\u304c\u8133\u306e\u6a5f\u80fd\u3092\u5909\u3048\u308b\u3068\u8a00\u3046\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3059\u3002\u3053\u306e\u5834\u5408\u3001\u4fb5\u5bb3\u523a\u6fc0\u3092\u9664\u53bb\u3059\u308b\u3068\u3001\u6700\u7d42\u7684\u306b\u3053\u308c\u3089\u306e\u51e6\u7406\u306f\u6b63\u5e38\u5316\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br>\u30c8\u30c3\u30d7\u30c0\u30a6\u30f3\u578b\u306f\u3001\u8133\u304b\u3089\u304f\u308b\u75bc\u75db\u3067\u3001\u8133\u5185\u306e\u5909\u5316\uff0c\u3055\u307e\u3056\u307e\u306a\u9069\u5fdc\u7684\u6d3b\u52d5\u5909\u5316\u306b\u3088\u3063\u3066\u3001\u75db\u307f\u306e\u904e\u654f\u304c\u751f\u3058\u308b\u3068\u3044\u3046\u3082\u306e\u3067\u3001\u306a\u3093\u3089\u304b\u306e\u8133\u5185\u306e\u72b6\u614b\u304c\u201c\u75db\u307f\u201d\u3068\u3044\u3046\u4f53\u9a13\u3092\u751f\u3080\u3068\u3044\u3046\u5834\u5408\u3092\u6307\u3057\u307e\u3059\u3002\u3053\u306e\u70ba\u3001\u30c8\u30c3\u30d7\u30c0\u30a6\u30f3\u578b\u306f\u3001\u75bc\u75db\u51e6\u7406\u306e\u5897\u5f37\u304c\u4fb5\u5bb3\u523a\u6fc0\u3068\u306f\u72ec\u7acb\u3057\u3066\u767a\u751f\u3057\u3001\u75bc\u75db\u304c\u7dad\u6301\u3055\u308c\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u6cbb\u7642<\/h2>\n\n\n\n<p>\u75bc\u75db\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u57fa\u672c\u7684\u306a\u8aac\u660e\u3068\u7406\u89e3\u304c\u5927\u5207\u3067\u3059\u3002\u305d\u3057\u3066\u3001\u6cbb\u7642\u306b\u304a\u3044\u3066\u306f\u3001\u60a3\u8005\u3068\u533b\u7642\u5f93\u4e8b\u8005\u3068\u306e\u9593\u306e\u5f37\u56fa\u306a\u30d1\u30fc\u30c8\u30ca\u30fc\u30b7\u30c3\u30d7\u304c\u3001\u60a3\u8005\u304c\u751f\u6d3b\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u306b\u3001\u4e0d\u53ef\u6b20\u3068\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u751f\u6d3b\u306e\u898b\u76f4\u3057<\/h2>\n\n\n\n<p>\u8eab\u4f53\u6d3b\u52d5\u306e\u5897\u52a0\u30fb\u7761\u7720\u306e\u8cea\u306e\u5411\u4e0a\u30fb\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u306a\u3069\u306e\u5065\u5eb7\u7684\u306a\u751f\u6d3b\u7fd2\u6163\u306b\u95a2\u3059\u308b\u63d0\u6848<br>\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u3001\u30e8\u30ac\u3001\u592a\u6975\u62f3\u3001\u937c\u7078\u3001\u6307\u5727\u3001\u30ab\u30a4\u30ed\u30d7\u30e9\u30af\u30c6\u30a3\u30c3\u30af\u7642\u6cd5\u306a\u3069\u591a\u304f\u306e\u975e\u85ac\u7269\u7642\u6cd5\u306e\u6709\u52b9\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u85ac\u7269\u7642\u6cd5\u306e\u9078\u629e\u80a2<\/h2>\n\n\n\n<p>\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6297\u708e\u75c7\u85ac\u3084\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\u306a\u3069\u306e\u5f93\u6765\u306e\u3044\u308f\u3086\u308b\u93ae\u75db\u85ac\u306f\u3001\u4e00\u822c\u7684\u306b\u52b9\u679c\u304c\u306a\u304f\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\uff08\u9ebb\u85ac\u3092\u542b\u3080\uff09\u306f\u3001\u907f\u3051\u308b\u3079\u304d\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u52b9\u679c\u7684\u306a\u85ac\u5264\u3068\u3057\u3066\u306f\u3001<br>\u30a2\u30df\u30c8\u30ea\u30d7\u30c1\u30ea\u30f3\u306a\u3069\u306e\u4e09\u74b0\u7cfb\u6297\u3046\u3064\u5264\u3001\u30c7\u30e5\u30ed\u30ad\u30bb\u30c1\u30f3\u3084\u30df\u30eb\u30ca\u30b7\u30d7\u30e9\u30f3\u306a\u3069\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u30fb\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u518d\u53d6\u308a\u8fbc\u307f\u963b\u5bb3\u85ac\uff08SNRI\uff09\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u518d\u53d6\u308a\u8fbc\u307f\u963b\u5bb3\u85ac\u3001\u304a\u3088\u3073\u30ac\u30d0\u30da\u30f3\u30c1\u30f3\u3001\u30d7\u30ec\u30ac\u30d0\u30ea\u30f3\u306a\u3069\u306e\u30ac\u30d0\u30da\u30f3\u30c1\u30ce\u30a4\u30c9\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u53c2\u8003\u6587\u732e<br>\u30fbNat Rev Neurol. 2024 Jun;20(6):347-363.<br>doi: 10.1038\/s41582-024-00966-8. Epub 2024 May 16. Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms Chelsea M Kaplan, Eoin Kelleher, Anushka Irani, Andrew Schrepf, Daniel J Clauw , Steven E Harte<br>\u30fbPain 2024 Nov1;165(11S):S50-S57.doi:10.1097\/\/j.pain.0000000000003305. The concept of nociplastic pain-where to from here? Eva Kosek<br>\u30fb\u9ebb\u91542026\uff1b75\uff1a152\u2015160\uff0e\u7279\u96c6\u6162\u6027\u75bc\u75db\u306b\u304a\u3051\u308b\u6700\u8fd1\u306e\u8a71\u984c\u3000\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u306e\u6700\u8fd1\u306e\u8a71\u984c\u3000\u52a0\u85e4\u3000\u7dcf\u592b<\/p>\n<\/blockquote>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"533\" src=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-11-800x533.png\" alt=\"\" class=\"wp-image-1144\" srcset=\"https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-11-800x533.png 800w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-11-400x267.png 400w, https:\/\/ito-pain.com\/blog\/wp-content\/uploads\/2026\/05\/image-11.png 876w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n<p>\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\uff08nociplastic pain\uff09\u3068\u3044\u3046\u6982\u5ff5\u304c\u3001\u5c0e\u5165\u306f\u3055\u308c\u305f\u3082\u306e\u306e\u3001\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u75db\u307f\u304c\u767a\u751f\u3057\u3066\u3044\u308b\u306e\u304b\u306b\u3064\u3044\u3066\u3001\u307e\u3060\u307e\u3060\u3088\u304f\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u3053\u3068\u304c\u591a\u304f\u5b58\u5728\u3057\u307e\u3059\u3002\u3088\u304f\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u306f\u3001\u5f53\u7136\u3001\u6cbb\u7642\u306b\u96e3\u6e0b\u3059\u308b\u308f\u3051\u3067\u3001\u5f53\u30da\u30a4\u30f3\u30af\u30ea\u30cb\u30c3\u30af\u306b\u6765\u9662\u3055\u308c\u3066\u3082\u601d\u3046\u3088\u3046\u306a\u6210\u679c\u304c\u5f97\u3089\u308c\u305a\u3001\u6765\u9662\u3055\u308c\u306a\u304f\u306a\u3063\u305f\u308a\u3001\u30c9\u30af\u30bf\u30fc\u30b7\u30e7\u30c3\u30d4\u30f3\u30b0\u3068\u3044\u308f\u308c\u308b\u3044\u308d\u3044\u308d\u306a\u533b\u7642\u65bd\u8a2d\u3092\u6e21\u308a\u6b69\u304f\u3088\u3046\u306a\u60a3\u8005\u3055\u3093\u3082\u591a\u304f\u3044\u307e\u3059\u3002\u75db\u307f\u3067\u6765\u9662\u3057\u305f\u306e\u306b\u3001\u6297\u3046\u3064\u85ac\u3084\u6297\u3066\u3093\u304b\u3093\u85ac\u3001\u6297\u4e0d\u5b89\u85ac\u304c\u51e6\u65b9\u3055\u308c\u308b\u3053\u3068\u306b\u62b5\u6297\u304c\u3042\u308b\u60a3\u8005\u3055\u3093\u3082\u591a\u304f\u304a\u3089\u308c\u307e\u3059\u3002<br>\u4eca\u56de\u306e\u30d6\u30ed\u30b0\u3067\u306f\u3001\u75db\u307f\u306f\u307e\u3060\u307e\u3060\u672a\u77e5\u306a\u3053\u3068\u304c\u591a\u304f\u3001\u96e3\u6cbb\u6027\u306e\u75db\u307f\u304c\u591a\u304f\u5b58\u5728\u3059\u308b\u3053\u3068\u3092\u5c11\u3057\u3067\u3082\u3054\u7406\u89e3\u3044\u305f\u3060\u3051\u308c\u3070\u3068\u8003\u3048\u3001\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u306b\u3064\u3044\u3066\u306e\u30d6\u30ed\u30b0\u3092\u66f8\u304b\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6162\u6027\u75bc\u75db\u306b\u304a\u3044\u3066\u306f\u3001\u3057\u3070\u3057\u3070\u75bc\u75db\u306e\u539f\u56e0\u3068\u306a\u308b\u4fb5\u8972\u304c\u53d6\u308a\u9664\u304b\u308c\u305f\u5f8c\u3084\u7d44\u7e54\u7684\u306b\u306f\u4fee\u5fa9\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u898b\u3048\u308b\u5834\u5408\u3001\u3082\u3057\u304f\u306f\u4fb5\u8972\u304c\u5168\u304f\u306a\u3044\u72b6\u614b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u75db\u307f\u304c\u767a\u751f\u3057&#8230;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"class_list":["post-1142","post","type-post","status-publish","format-standard","hentry","category-4"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/posts\/1142","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/comments?post=1142"}],"version-history":[{"count":1,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/posts\/1142\/revisions"}],"predecessor-version":[{"id":1148,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/posts\/1142\/revisions\/1148"}],"wp:attachment":[{"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/media?parent=1142"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/categories?post=1142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}