{"id":1115,"date":"2026-04-30T08:10:51","date_gmt":"2026-04-29T23:10:51","guid":{"rendered":"https:\/\/ito-pain.com\/blog\/?p=1115"},"modified":"2026-04-30T08:44:09","modified_gmt":"2026-04-29T23:44:09","slug":"post-1115","status":"publish","type":"post","link":"https:\/\/ito-pain.com\/blog\/post-1115\/","title":{"rendered":"\u75db\u98a8\u767a\u4f5c\uff1a\u75db\u98a8\u767a\u4f5c\u6642\u306e\u6cbb\u7642\u65b9\u6cd5\u3068\u3069\u306e\u7a0b\u5ea6\u8840\u6db2\u4e2d\u306e\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308c\u3070\u6c88\u7740\u3057\u305f\u5c3f\u9178\u7d50\u6676\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u304b\u306b\u3064\u3044\u3066"},"content":{"rendered":"\n

\u3044\u3068\u3046\u30da\u30a4\u30f3\u30af\u30ea\u30cb\u30c3\u30af\u306e\u9662\u9577\u306e\u4f0a\u85e4\u3067\u3059\u3002\u539a\u751f\u52b4\u50cd\u7701\u304c\u6bce\u5e74\u884c\u3063\u3066\u3044\u308b\u300c\u56fd\u6c11\u751f\u6d3b\u57fa\u790e\u8abf\u67fb\u300d\u306e\u4ee4\u548c4\u5e74(2022)\u306e\u8abf\u67fb\u306b\u3088\u308b\u3068\u3001\u73fe\u5728\u3001\u75db\u98a8\u306e\u6cbb\u7642\u3067\u901a\u9662\u3057\u3066\u3044\u308b\u60a3\u8005\u7dcf\u6570\u306f\u7d04130\u4e076\u5343\u4eba\uff08\u7537\u6027123\u4e076\u5343\u4eba\u3001\u5973\u60277\u4e07\u4eba\uff09\u3067\u3042\u308a\u3001\u9ad8\u5c3f\u9178\u8840\u75c7\u306e\u60a3\u8005\u6570\u306f\u3001\u7d041,300\u4e07\u4eba\u3068\u63a8\u6e2c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5f53\u9662\u3067\u3082\u75db\u98a8\u767a\u4f5c\u3067\u60a3\u8005\u3055\u3093\u304c\u6765\u9662\u3055\u308c\u307e\u3059\u306e\u3067\u3001\u5f53\u9662\u3067\u306e\u6cbb\u7642\u5185\u5bb9\u306b\u3064\u3044\u3066\u7c21\u5358\u306b\u3054\u8aac\u660e\u3057\u3001\u75db\u98a8\u767a\u4f5c\u5f8c\u306e\u8840\u4e2d\u5c3f\u9178\u5024\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306b\u3064\u3044\u3066\u306e\u8a71\u3092\u3057\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u306f\u3058\u3081\u306b<\/strong><\/h2>\n\n\n\n

\u75db\u98a8\u767a\u4f5c\u3068\u306f\uff1a\u9ad8\u5c3f\u9178\u8840\u75c7\u304c\u6301\u7d9a\u3059\u308b\u3068\u95a2\u7bc0\u5185\u306b\u5c3f\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u306e\u7d50\u6676\u304c\u6790\u51fa\u3057\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u767d\u8840\u7403\u3068\u3044\u3046\u7d30\u80de\u304c\u6d3b\u6027\u5316\u3057\u3001\u6025\u6027\u708e\u75c7\uff08\u6025\u6027\u95a2\u7bc0\u708e\uff09\u306b\u3088\u308b\u75bc\u75db\u304c\u751f\u3058\u305f\u5834\u5408\u3092\u75db\u98a8\u767a\u4f5c\u3068\u3044\u3044\u307e\u3059\u3002<\/p>\n\n\n

\n
\"\"
\u6ed1\u6db2\u4e2d\u306e\u5c3f\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7\u504f\u5149\u9855\u5fae\u93e1\u50cf\uff1a<\/strong>
\u5c3f\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u7d50\u6676\u5de6\u56f3\u306f\u03bb\u8ef8\u306b\u5782\u76f4\u306a\u65b9\u5411\u3001\u53f3\u56f3\u306f\u03bb\u8ef8\u306b\u5e73\u884c\u306a\u65b9\u5411\u3067\u64ae\u5f71<\/strong><\/figcaption><\/figure>\n<\/div>\n\n\n
\n

Lancet. 2021 May 15;397(10287):1843-1855. doi: 10.1016\/S0140-6736(21)00569-9. Epub 2021 Mar 30. Gout <\/strong>Nicola Dalbeth<\/a>, Anna L Gosling<\/a>, Angelo Gaffo<\/a>, Abhishek Abhishek<\/a>\u3088\u308a\u629c\u7c8b<\/strong><\/p>\n<\/blockquote>\n\n\n\n

\u75db\u98a8\u306e\u767a\u751f\u5834\u6240\u306b\u3064\u3044\u3066<\/h2>\n\n\n\n

\u901a\u5e38\uff0c1 \u30ab\u6240\u306e\u95a2\u7bc0\u306b\u767a\u75c7\u3059\u308b\u5358\u95a2\u7bc0\u708e\u3067\uff0c\u6bcd\u8dbe\u57fa\u95a2\u7bc0\uff08\u6bcd\u8dbe\u306e\u4ed8\u3051\u6839\u90e8\u5206\uff09\u306b\u521d\u767a\u30676 \u5272\u3001\u5168\u7d4c\u904e\u4e2d\u3067\u306f9 \u5272\u304c\u767a\u75c7\u3059\u308b\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002\u6bcd\u8dbe\u4ee5\u5916\u3067\u306f\u3001\u4ed6\u306e\u8db3\u8dbe\u3084\u8db3\u95a2\u7bc0\u3001\u819d\u95a2\u7bc0\u306a\u3069\u3082\u597d\u767a\u90e8\u4f4d\u3067\u3001\u624b\u6307\u95a2\u7bc0\u3001\u624b\u9996\u95a2\u7bc0\u3001\u8098\u95a2\u7bc0\u306a\u3069\u306b\u3082\u767a\u75c7\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u75db\u98a8\u306e\u7d4c\u904e\u306b\u3064\u3044\u3066<\/h2>\n\n\n\n

\u75db\u98a8\u767a\u4f5c\u306f\u3057\u3070\u3057\u3070\u65e9\u671d\u306b\u51fa\u73fe\u3057\u3001\u6570\u6642\u9593\u3082\u3059\u308b\u3068\u5c40\u6240\u306e\u8457\u660e\u306a\u767a\u8d64\u816b\u8139\u304c\u51fa\u73fe\u3057\u3001\u6fc0\u3057\u3044\u75bc\u75db\u3092\u4f34\u3044\u307e\u3059(\u56f31)\u3002\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u4f5c\u7528\u3067\u767a\u71b1\u3084\u60aa\u5bd2\u306a\u3069\u306e\u5168\u8eab\u75c7\u72b6\u3082\u751f\u3058\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u75db\u98a8\u767a\u4f5c\u306f\u3001\u4e88\u5146\u306e\u51fa\u73fe\u304b\u3089\u30d4\u30fc\u30af\u307e\u3067\u304c\u6975\u3081\u3066\u77ed\u6642\u9593\uff08\uff112 \u6642\u9593\u7a0b\u5ea6\uff09\u3067\u3042\u308b\u3053\u3068\u304c\u7279\u5fb4\u3067\u3059\u304c\u30012\uff5e\uff13 \u9031\u9593\u307b\u3069\u3067\u81ea\u7136\u306b\u8efd\u5feb\u3057\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u7121\u6cbb\u7642\u306e\u5834\u5408\u3001\u6700\u521d\u306e3\u65e5\u9593\u306f\u3001\u75bc\u75db\u304c\u8efd\u6e1b\u305b\u305a\u7d99\u7d9a\u3057\u30017\u65e5\u5f8c\u3082\u75db\u307f\u304c\u7d9a\u304f\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u75db\u98a8\u767a\u4f5c\u306f\u6700\u521d1\uff5e2 \u5e74\u306b1 \u56de\u7a0b\u5ea6\u306e\u983b\u5ea6\u3067\u767a\u75c7\u3059\u308b\u5358\u95a2\u7bc0\u708e\u3067\u3001\u975e\u767a\u4f5c\u671f\u306b\u306f\u5168\u304f\u7121\u75c7\u5019\u3068\u306a\u308a\u307e\u3059\u3002\u3068\u3044\u3063\u3066\u3082\u3001\u305d\u306e\u307e\u307e\u9ad8\u5c3f\u9178\u8840\u75c7\u3092\u653e\u7f6e\u3059\u308b\u3068\u6b21\u7b2c\u306b\u767a\u4f5c\u306e\u9593\u9694\u304c\u77ed\u304f\u306a\u308a\u3001\u3064\u3044\u306b\u306f\u524d\u306e\u767a\u4f5c\u304c\u5b8c\u5168\u306b\u6cbb\u307e\u3089\u306a\u3044\u3046\u3061\u306b\u5225\u306e\u95a2\u7bc0\u306b\u65b0\u305f\u306a\u767a\u4f5c\u3092\u7e70\u308a\u8fd4\u3059\u591a\u767a\u6027\u95a2\u7bc0\u708e\u3068\u306a\u308a\u3001\u975e\u767a\u4f5c\u671f\u3067\u3082\u75db\u307f\u304c\u6301\u7d9a\u3059\u308b\u6162\u6027\u75db\u98a8\u306b\u9032\u884c\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u6162\u6027\u75db\u98a8\u3067\u306f\uff0c\u75db\u98a8\u767a\u4f5c\u3092\u7e70\u308a\u8fd4\u3059\u95a2\u7bc0\u306a\u3069\u306b\u75db\u98a8\u7d50\u7bc0\u304c\u51fa\u73fe\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059(\u56f32)\u3002\u307e\u305f\u3053\u306e\u6642\u671f\u306b\u306f\uff0c\u5c3f\u8def\u7d50\u77f3\u3084\u814e\u6a5f\u80fd\u969c\u5bb3\u306a\u3069\u3092\u3057\u3070\u3057\u3070\u5408\u4f75\u3057\u307e\u3059\u3002\u5c3f\u8def\u7d50\u77f3\u306b\u3064\u3044\u3066\u306f\u75db\u98a8\u767a\u4f5c\u306b\u5148\u884c\u3057\u3066\u767a\u75c7\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n

\n
\"\"
\u56f31 \u6bcd\u8dbe\u57fa\u95a2\u7bc0\u306e\u75db\u98a8\u95a2\u7bc0\u708e\u3000 \u56f32 \u6bcd\u8dbe\u57fa\u95a2\u7bc0\u306e\u75db\u98a8\u7d50\u7bc0<\/figcaption><\/figure>\n<\/div>\n\n\n
\n

\u56f3\u3000\u65e5\u672c\u81e8\u724082 \u5dfb6 \u53f7(2024-6)\u3000907\uff0d911 \u7279\u96c6\uff1a\u9ad8\u5c3f\u9178\u8840\u75c72024\u3000 III\uff0e\u9ad8\u5c3f\u9178\u8840\u75c7\u306e\u81e8\u5e8a\u9ad8\u5c3f\u9178\u8840\u75c7\u306e\u6cbb\u7642\u85ac\u7269\u7642\u6cd5\u3000\u75db\u98a8\u767a\u4f5c\u6cbb\u7642\u85ac\u3000\u5927\u5c71\u535a\u53f8\u3000\u3088\u308a\u629c\u7c8b<\/p>\n<\/blockquote>\n\n\n\n

\u767a\u4f5c\u6642\u306f\u3001\u60a3\u90e8\u3092\u6319\u4e0a\u3059\u308b\u3001\u75bc\u75db\u90e8\u5206\u306b\u8ca0\u8377\u304c\u304b\u304b\u3089\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u3001\u51b7\u3084\u3059\u306a\u3069\u304c\u75bc\u75db\u306e\u5bfe\u51e6\u7642\u6cd5\u3068\u3057\u3066\u3042\u3052\u3089\u308c\u307e\u3059\u3002\u5f8c\u3001\u7981\u9152\u3082\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n

\u75db\u98a8\u767a\u4f5c\u6cbb\u7642\u306e\u7b2c\u4e00\u306e\u76ee\u6a19\u306f\u3001\u8fc5\u901f\u306b\u95a2\u7bc0\u708e\u3092\u6d88\u9000\u3055\u305b\u3066QOL\uff08\u751f\u6d3b\u306e\u8cea\uff09\u306e \u4f4e\u4e0b\u3092\u6700\u5c0f\u9650\u306b\u3059\u308b\u3053\u3068\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\n

\u53c2\u8003\u6587\u732e<\/strong><\/p>\n\n\n\n

\uff11\uff09\u65e5\u672c\u81e8\u724082 \u5dfb6 \u53f7(2024-6)\u3000907\uff0d911 \u7279\u96c6\uff1a\u9ad8\u5c3f\u9178\u8840\u75c72024\u3000 III\uff0e\u9ad8\u5c3f\u9178\u8840\u75c7\u306e\u81e8\u5e8a\u9ad8\u5c3f\u9178\u8840\u75c7\u306e\u6cbb\u7642\u85ac\u7269\u7642\u6cd5\u3000\u75db\u98a8\u767a\u4f5c\u6cbb\u7642\u85ac\u3000\u5927\u5c71\u535a\u53f8<\/p>\n\n\n\n

\uff12\uff09Am J Med. 1987 Mar;82(3):421-6. doi: 10.1016\/0002-9343(87)90441-4.<\/p>\n\n\n\n

Asymptomatic hyperuricemia. Risks and consequences in the Normative Aging Study<\/p>\n\n\n\n

E W Campion<\/a>, R J Glynn<\/a>, L O DeLabry<\/a><\/p>\n<\/blockquote>\n\n\n\n

\u5f53\u9662\u3067\u306e\u6cbb\u7642<\/h2>\n\n\n\n

\u554f\u8a3a\u21d2\u8996\u8a3a\u21d2\u900f\u8996\u4e0b\u75bc\u75db\u90e8\u4f4d\u30ec\u30f3\u30c8\u30b2\u30f3\u64ae\u5f71\u30fb\u8840\u6db2\u691c\u67fb\uff08\u5c3f\u9178\u5024\u3084\u708e\u75c7\u75c7\u72b6\u3092\u30c1\u30a7\u30c3\u30af\uff09<\/p>\n\n\n\n

\u21d2\u6cbb\u7642<\/p>\n\n\n\n

\u30fb\u30b9\u30c6\u30ed\u30a4\u30c9\uff0b\u5c40\u6240\u9ebb\u9154\u85ac\u306e\u6ce8\u5c04<\/p>\n\n\n\n

\u75db\u98a8\u767a\u4f5c\u6642\u306e\u75db\u307f\u306b\u5bfe\u3057\u3066\u75bc\u75db\u7de9\u548c\u306e\u70ba\u306b\u884c\u3046\u3053\u3068\u3068\u3057\u3066\u6ce8\u5c04\u53ef\u80fd\u3068\u5224\u65ad\u3057\u305f\u5834\u5408\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u3068\u5c40\u6240\u9ebb\u9154\u85ac\u3092\u75bc\u75db\u90e8\u4f4d\u306b\u6ce8\u5c04\uff08\u900f\u8996\u64ae\u5f71\u4e0b\u3067\u30d4\u30f3\u30dd\u30a4\u30f3\u30c8\u306b\u85ac\u3092\u6ce8\u5165\uff09\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u30fb\u5185\u670d\u85ac\u306e\u51e6\u65b9<\/p>\n\n\n\n

\u75bc\u75db\u304c\u304b\u306a\u308a\u5f37\u3044\u5834\u5408\u306f\u3001\u30d7\u30ec\u30c9\u30cb\u30f3\u306a\u3069\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u5185\u670d\u3092\u8003\u616e\u3057\u307e\u3059\u304c\u3001\u307e\u305a\u306fNSAID\uff53\uff08\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6297\u708e\u75c7\u85acNSAIDs\uff1a\u30ca\u30d7\u30ed\u30ad\u30bb\u30c1\u30f3\uff08\u30ca\u30a4\u30ad\u30b5\u30f3\ud83c\udd2c\uff1a\u521d\u56de600\u338e\u3001\u305d\u306e\u5f8c1\u56de300\u338e1\u65e52\u56de\uff09\u3001\u30ed\u30ad\u30bd\u30cb\u30f3\u3084\u30b8\u30af\u30ed\u30d5\u30a7\u30ca\u30af\u306a\u3069\uff09\u3092\u80c3\u7c98\u819c\u4fdd\u8b77\u5264\u3068\u3068\u3082\u306b\u51e6\u65b9\u3057\u307e\u3059\uff08\u305f\u3060\u3057\u3001NSAID\uff53\u306f\u814e\u6a5f\u80fd\u969c\u5bb3\u304c\u3042\u308b\u4eba\u306b\u306f\u4f7f\u7528\u3092\u63a7\u3048\u307e\u3059\uff09\u3002<\/p>\n\n\n\n

\u75db\u98a8\u767a\u4f5c\u4e88\u9632\u306e\u305f\u3081\u3001\u30b3\u30eb\u30d2\u30c1\u30f3\u3092\u5c11\u91cf\uff080.5\u338e\uff09\u4f75\u7528\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u30b3\u30eb\u30d2\u30c1\u30f3\u306e\u4f5c\u7528\u6a5f\u5e8f\u3067\u3059\u304c\u3001\u75db\u98a8\u767a\u4f5c\u306e\u539f\u56e0\u3068\u306a\u308b\u767d\u8840\u7403\u304c\u95a2\u7bc0\u5185\u306e\u5c3f\u9178\u306b\u4f5c\u7528\u3059\u308b\u306e\u3092\u6291\u3048\u3001\u75db\u98a8\u767a\u4f5c\u3092\u6291\u5236\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u751f\u7269\u5b66\u7684\u88fd\u5264\uff08\u6d77\u5916\uff09<\/p>\n\n\n\n

\u767d\u8840\u7403\u904a\u8d70\u963b\u6b62\u3084\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3(interleukin\uff1aIL)-1 \u7523\u751f\u6291\u5236\u304c\u4f5c\u7528\u6a5f\u5e8f\u3067\u3042\u308b\u3068\u5206\u304b\u3063\u3066\u304d\u305f\u305f\u3081\u3001IL-1 \u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u3057\u305f\u751f\u7269\u5b66\u7684\u88fd\u5264\u3082\u75db\u98a8\u95a2\u7bc0\u708e\u306b\u8a66\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u304c\u3001\u65e5\u672c\u3067\u306f\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

\u75bc\u75db\u304c\u7de9\u548c\u3057\u305f\u5f8c\u306b\u8840\u4e2d\u306e\u9ad8\u5c3f\u9178\u5024\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u305f\u3081\u306e\u5185\u670d\u85ac\u306e\u51e6\u65b9\u3092\u884c\u3044\u307e\u3059\uff08\u6642\u306b\u5c11\u91cf\u304b\u3089\u540c\u6642\u51e6\u65b9\u3057\u307e\u3059\uff09\u3002<\/p>\n\n\n\n

\u5c3f\u9178\u5024\u306e\u76ee\u6a19\u5024\u306b\u3064\u3044\u3066<\/h2>\n\n\n\n

\u5c3f\u9178\u306e\u751f\u4f53\u5185\u3067\u306e\u6eb6\u89e3\u5ea6\u306f6.7 mg\/dL \u524d\u5f8c\u3067\u3042\u308a\u3001\u3053\u308c\u3092\u8d85\u3048\u308b\u3068\u5c3f\u9178\u30ca\u30c8\u30ea\u30a6\u30e0 \u7d50\u6676\u306e\u6790\u51fa\u304c\u8d77\u3053\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9ad8\u5c3f\u9178\u8840\u75c7\u306f\u75db\u98a8\u767a\u75c7\u306e\u5fc5\u9808\u6761\u4ef6\u3067\u3001\u8840\u4e2d\u306e\u5c3f\u9178\u5024\u304c\u9ad8\u3044\u307b\u3069\u3001\u307e\u305f\u9ad8\u5c3f\u9178\u8840\u75c7\u306e\u671f\u9593\u304c\u9577\u3044\u307b\u3069\u75db\u98a8\u767a\u4f5c\u3092\u767a\u75c7\u3059\u308b\u983b\u5ea6\u306f\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u8840\u4e2d\u306e\u5c3f\u9178\u5024\u304c9 mg\/dL \u4ee5\u4e0a\u3067\u306f\u3001\u305d\u306e\u5f8c5 \u5e74\u9593\u306b\u75db\u98a8\u767a\u4f5c\u304c\u751f\u3058\u308b\u53ef\u80fd\u6027\u306f20\uff05\u4ee5\u4e0a\u306b\u4e0a\u6607\u3059\u308b\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u75db\u98a8\u767a\u4f5c\u306b\u306f\u3001\u9ad8\u5c3f\u9178\u8840\u75c7\u4ee5\u5916\u306b\u5e74\u9f62\u3001\u80a5\u6e80\u3001\u9ad8\u8840\u5727\u3001\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u30ec\u30d9\u30eb\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u6442\u53d6\u304c\u30ea\u30b9\u30af\u56e0\u5b50\u3068\u3057\u3066\u6319\u3052\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u300c\u9ad8\u5c3f\u9178\u8840\u75c7\u30fb\u75db\u98a8\u306e\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 \u7b2c\uff13\u7248\uff082018\u5e74\uff09\u304a\u3088\u3073\u305d\u306e\u8ffd\u88dc\u7248\uff082022\u5e74\uff09\u300d\u306b\u3088\u308b\u3068\u75db\u98a8\u7d50\u7bc0\u304c\u3042\u308b\u5834\u5408\u3082\u542b\u3081\u3066\u3001\u5c3f\u9178\u5024\uff16mg\/dL\u4ee5\u4e0b\u306b\u3059\u308b\u306e\u304c\u671b\u307e\u3057\u3044\u3068\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u307e\u305f\u3001\u9ad8\u5c3f\u9178\u8840\u75c7\u306f\u3001\u75db\u98a8\u767a\u4f5c\u306e\u307f\u3067\u306a\u304f\u5c3f\u8def\u5168\u4f53\u306e\u7d50\u77f3\u306e\u539f\u56e0\u306b\u306a\u308a\u307e\u3059\u306e\u3067\u3001\u5c3f\u9178\u5024\u304c8.0\u338e\/dl\u4ee5\u4e0a\u306e\u5834\u5408\u306f\u3001\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308b\u6cbb\u7642\u3092\u304a\u52e7\u3081\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\n

\u53c2\u8003\u6587\u732e<\/p>\n\n\n\n

Am J Med. 1987 Mar;82(3):421-6. doi: 10.1016\/0002-9343(87)90441-4.<\/p>\n\n\n\n

Asymptomatic hyperuricemia. Risks and consequences in the Normative Aging Study<\/p>\n\n\n\n

E W Campion<\/a>, R J Glynn<\/a>, L O DeLabry<\/a><\/p>\n<\/blockquote>\n\n\n\n

\u5c3f\u9178\u3092\u4e0b\u3052\u308b\u85ac\u5264\u306b\u3064\u3044\u3066\u306f\u3001\u5927\u304d\u304f\u5c3f\u9178\u751f\u6210\u6291\u5236\u85ac\u3068\u5c3f\u9178\u6392\u51fa\u4fc3\u9032\u85ac\u304c\u3042\u308a\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308b\u85ac\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u5c3f\u9178\u751f\u6210\u6291\u5236\u85ac\u30fb\u30fb\u30fb\u307e\u305a\u306f\u6cbb\u7642\u3068\u3057\u3066\u306f\u3001\u5c3f\u9178\u751f\u6210\u6291\u5236\u85ac\u3092\u5c11\u91cf\u304b\u3089\u958b\u59cb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u30fb\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\uff08\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u9320\ud83c\udd2c50\u338e\u30fb100\u338e\uff09\u30fb\u30fb\u30fb\u30d7\u30ea\u30f3\u578b\u30ad\u30b5\u30f3\u30c1\u30f3\u9178\u5316\u9084\u5143\u9175\u7d20\u963b\u5bb3\u85ac\u3067\u3042\u308a\u3001\u9069\u5fdc\u75be\u60a3\u306f\u3001\u9ad8\u5c3f\u9178\u8840\u75c7\u30fb\u9ad8\u8840\u5727\u3092\u5408\u4f75\u3057\u305f\u75db\u98a8\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u5c3f\u9178\u304c\u751f\u6210\u3059\u308b\u306e\u3092\u9632\u3044\u3067\u304f\u308c\u307e\u3059\u304c\u3001\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u306f\u814e\u6a5f\u80fd\u4f4e\u4e0b\u3092\u6291\u5236\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u30e1\u30eb\u30ab\u30d7\u30c8\u30d7\u30ea\u30f3\u307e\u305f\u306f\u30a2\u30b6\u30c1\u30aa\u30d7\u30ea\u30f3\u3068\u306e\u4f75\u7528\u306f\u3001\u9aa8\u9ac4\u6291\u5236\u306a\u3069\u306e\u526f\u4f5c\u7528\u304c\u5897\u5f37\u3055\u308c\u308b\u305f\u3081\u7981\u5fcc\u3068\u306a\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u85ac\u5264\u904e\u654f\u6027\u904e\u654f\u75c7\u306e\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u6295\u4e0e\u4e2d\u306b\u76ae\u75b9\u304c\u8a8d\u3081\u3089\u308c\u305f\u5834\u5408\u306f\u3001\u3059\u3050\u306b\u85ac\u5264\u3092\u4e2d\u6b62\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u901a\u5e38100\u338e\/\u65e5\u3067\u958b\u59cb\u3057\u307e\u3059\u304c\u3001\u814e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u6295\u4e0e\u91cf\u306e\u6e1b\u91cf\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n

\u4ee5\u4e0b\u306b\u9ad8\u5c3f\u9178\u8840\u75c7\u30fb\u75db\u98a8\u306e\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u7b2c\uff13\u72482022\u5e74\u8ffd\u88dc\u7248\u3088\u308a\u629c\u7c8b\u3057\u305f\u63a8\u5968\u4f7f\u7528\u91cf\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\uff15\uff10ml\u814e\u6a5f\u80fd<\/th>\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u6295\u4e0e\u91cf<\/th><\/tr><\/thead>
Ccr \uff1e 50\u217fL\/\u5206<\/td>100\uff5e300mg\/\u65e5<\/td><\/tr>
30mL\/\u5206 \uff1c Ccr \u2266 50\u217fL\/\u5206<\/td>100mg\/\u65e5<\/td><\/tr>
Ccr \u2266 30\u217fL\/\u5206<\/td>50mg\/\u65e5<\/td><\/tr>
\u8840\u6db2\u900f\u6790\u65bd\u884c\u4f8b<\/td>\u900f\u6790\u7d42\u4e86\u6642\u306b100mg<\/td><\/tr>
\u8179\u819c\u900f\u6790\u65bd\u884c\u4f8b<\/td>50mg\/\u65e5<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Ccr\uff1a\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u30af\u30ea\u30a2\u30e9\u30f3\u30b9<\/p>\n\n\n\n

Ccr\u226630\uff4d\uff4c\/\u5206\uff1b\u91cd\u75c7\u306e\u814e\u6a5f\u80fd\u969c\u5bb3\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u30fb\u30d5\u30a7\u30d6\u30ad\u30bd\u30b9\u30bf\u30c3\u30c8\uff08\u30d5\u30a7\u30d6\u30ea\u30af\ud83c\udd2c10\u338e\u30fb20\u338e\u30fb40\u338e\uff09\u30fb\u30fb\u30fb\u975e\u30d7\u30ea\u30f3\u578b\u30ad\u30b5\u30f3\u30c1\u30f3\u9178\u5316\u9084\u5143\u9175\u7d20\u963b\u5bb3\u85ac\u3067\u3001\u30a2\u30ed\u30d7\u30ea\u30ce\u30fc\u30eb\u540c\u69d8\u3001\u5c3f\u9178\u751f\u6210\u6291\u5236\u5264\u3067\u3059\u3002\u9069\u5fdc\u75be\u60a3\u306f\u3001\u9ad8\u5c3f\u9178\u8840\u75c7\u307e\u305f\u306f\u3001\u75db\u98a8\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u4e3b\u306b\u809d\u81d3\u4ee3\u8b1d\u306e\u85ac\uff08\u80c6\u6c41\u304b\u3089\u306e\u6392\u51fa\u7d4c\u8def\uff09\u3067\u3042\u308b\u305f\u3081\u3001\u4e2d\u7b49\u5ea6\u7a0b\u5ea6\u306e\u814e\u6a5f\u80fd\u969c\u5bb3\u304c\u3042\u3063\u305f\u5834\u5408\u3067\u3082\uff08\u5177\u4f53\u7684\u306a\u6570\u5024\u3068\u3057\u3066\u300130ml\/\u5206\uff1cCcr\u226650ml\/\u5206\uff09\u7528\u91cf\u8abf\u6574\u306f\u4e0d\u8981\u3067\u3059\u3002<\/p>\n\n\n\n

\u30e1\u30eb\u30ab\u30d7\u30c8\u30d7\u30ea\u30f3\u307e\u305f\u306f\u30a2\u30b6\u30c1\u30aa\u30d7\u30ea\u30f3\u3068\u306e\u4f75\u7528\u306f\u3001\u9aa8\u9ac4\u6291\u5236\u306a\u3069\u306e\u526f\u4f5c\u7528\u304c\u5897\u5f37\u3055\u308c\u308b\u305f\u3081\u7981\u5fcc\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u30fb\u30c8\u30d4\u30ed\u30ad\u30ed\u30b9\u30bf\u30c3\u30c8\uff08\u30c8\u30d4\u30ed\u30ea\u30c3\u30af\ud83c\udd2c20\u338e\u30fb40\u338e\u30fb60\u338e\uff09\u3082\u5c3f\u9178\u751f\u6210\u6291\u5236\u5264\u3067\u3059\u3002\u30d5\u30a7\u30d6\u30ad\u30bd\u30b9\u30bf\u30c3\u30c8\u540c\u69d8\u306b\u3001\u975e\u30d7\u30ea\u30f3\u578b\u30ad\u30b5\u30f3\u30c1\u30f3\u9178\u5316\u9084\u5143\u9175\u7d20\u963b\u5bb3\u85ac\u3067\u3001\u9069\u5fdc\u75be\u60a3\u306f\u3001\u9ad8\u5c3f\u9178\u8840\u75c7\u307e\u305f\u306f\u3001\u75db\u98a8\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u5c3f\u9178\u6392\u51fa\u4fc3\u9032\u85ac<\/h2>\n\n\n\n

\u975e\u9078\u629e\u7684\u5c3f\u9178\u518d\u5438\u53ce\u963b\u5bb3\u5264<\/h3>\n\n\n\n

\u30fb\u30d9\u30f3\u30ba\u30d6\u30ed\u30de\u30ed\u30f3\uff08\u30e6\u30ea\u30ce\u30fc\u30e0\ud83c\udd2c25\u338e\uff09\u3000<\/p>\n\n\n\n

\u814e\u81d3\u306e\u8fd1\u4f4d\u5c3f\u7d30\u7ba1\u3068\u8a00\u3046\u5834\u6240\u306b\u50cd\u3044\u3066\u3001\u5c3f\u4e2d\u3078\u5c3f\u9178\u3092\u6392\u51fa\u4fc3\u9032\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u6dfb\u4ed8\u6587\u66f8\u4e0a\u306f\u3001\u75db\u98a8\u3001\u9ad8\u5c3f\u9178\u8840\u75c7\u3092\u4f34\u3046\u9ad8\u8840\u5727\u75c7\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u9ad8\u9f62\u8005\u306f25\u338e\u304b\u3089\u3001\u901a\u5e3850\u338e\u304b\u3089\u958b\u59cb\u3057\u3001\u5897\u91cf\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n

CYP2C9\u3068\u8a00\u3046\u809d\u81d3\u306e\u4ee3\u8b1d\u9175\u7d20\u3092\u963b\u5bb3\u3057\u3001\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u306e\u4f5c\u7528\u304c\u3001\u5897\u5f37\u3059\u308b\u5834\u5408\u304c\u3042\u308a\u3001\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u809d\u708e\u306e\u767a\u751f\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u5c11\u306a\u304f\u3068\u3082\uff16\u30ab\u6708\u9593\u306f\u3001\u5b9a\u671f\u7684\u306a\u8840\u6db2\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3042\u308b\u3068\u539a\u751f\u52b4\u50cd\u7701\u304b\u3089\u52e7\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u5c3f\u4e2d\u5c3f\u9178\u6fc3\u5ea6\u304c\u4e0a\u304c\u308b\u3068\u5c3f\u9178\u7d50\u77f3\u75c7\u304c\u5897\u5f37\u3059\u308b\u70ba\u3001\u6c34\u5206\u6442\u53d6\u3092\u591a\u3081\u306b\u6442\u53d6\u3057\u3066\u3082\u3089\u3044\u3001\u5c3f\u3092\u30a2\u30eb\u30ab\u30ea\u5316\u3059\u308b\u30af\u30a8\u30f3\u9178\u30ab\u30ea\u30a6\u30e0\u30fb\u30af\u30a8\u30f3\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u6c34\u548c\u7269\uff08\u30a6\u30e9\u30ea\u30c3\u30c9\ud83c\udd2c\uff096\u9320\u5206\uff13\/\u65e5\u3092\u540c\u6642\u306b\u51e6\u65b9\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u305d\u306e\u4ed6\u306e\u5c3f\u9178\u6392\u51fa\u4fc3\u9032\u4f5c\u7528\u85ac\u306b\u3064\u3044\u3066<\/h3>\n\n\n\n

\u9ad8\u8840\u5727\u85ac\u306e\u30ed\u30b5\u30eb\u30bf\u30f3\u30ab\u30ea\u30a6\u30e0\uff08\u30ed\u30b5\u30eb\u30bf\u30f3\u30ab\u30ea\u30a6\u30e0\ud83c\udd2c\uff09\uff08ARB\uff09\u3084\u9ad8\u8102\u8840\u75c7\u85ac\u306e\u30d5\u30a7\u30ce\u30d5\u30a3\u30d6\u30e9\u30fc\u30c8\uff08\u30d5\u30a7\u30ce\u30d5\u30a3\u30d6\u30e9\u30fc\u30c8\ud83c\udd2c\uff09\u306b\u3082\u5c3f\u9178\u6392\u51fa\u4fc3\u9032\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u3053\u306e\u3053\u3068\u304b\u3089\u3001\u9ad8\u8840\u5727\u3084\u9ad8\u8102\u8840\u75c7\u306e\u5408\u4f75\u75c7\u304c\u3042\u308b\u5834\u5408\u306e\u4f7f\u7528\u3092\u8003\u616e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u9078\u629e\u7684\u5c3f\u9178\u518d\u5438\u53ce\u963b\u5bb3\u5264<\/h3>\n\n\n\n

\u30fb\u30c9\u30c1\u30cc\u30e9\u30c9\uff08\u30e6\u30ea\u30b9\ud83c\udd2c0.5\u338e\u30fb1\u338e\u30fb2\u338e\uff09<\/p>\n\n\n\n

2020\u5e74\u306b\u767a\u58f2\u3055\u308c\u305f\u65b0\u3057\u3044\u85ac\u3067\u3059\u3002\u30c9\u30c1\u30cc\u30e9\u30c9\u306f\u9078\u629e\u7684\u5c3f\u9178\u518d\u5438\u53ce\u963b\u5bb3\u5264\u3067\u3001\u814e\u81d3\u3067\u306e\u9078\u629e\u7684\u306b\u5c3f\u9178\u518d\u5438\u53ce\u963b\u5bb3\u306b\u52a0\u3048\u3001\u8178\u7ba1\u3067\u306e\u5c3f\u9178\u6392\u51fa\u3092\u963b\u5bb3\u3057\u306a\u3044\u3053\u3068\u304b\u3089\u814e\u81d3\u3067\u306e\u5c3f\u9178\u6392\u51fa\u306b\u904e\u5270\u306a\u8ca0\u8377\u3092\u4e0e\u3048\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u30c9\u30c1\u30cc\u30e9\u30c92\u338e\/\u65e5\u306f\u30d5\u30a7\u30d6\u30ad\u30bd\u30b9\u30bf\u30c3\u30c840\u338e\/\u65e5\u3001\u30d9\u30f3\u30ba\u30d6\u30ed\u30de\u30ed\u30f350\u338e\/\u65e5\u3068\u540c\u7b49\u306e\u5c3f\u9178\u964d\u4e0b\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u5c3f\u9178\u5206\u89e3\u9175\u7d20\u85ac<\/h3>\n\n\n\n

\u30fb\u30e9\u30b9\u30d6\u30ea\u30ab\u30fc\u30bc\uff08\u30e9\u30b9\u30ea\u30c6\u30c3\u30af\ud83c\udd2c\uff09\u30fb\u30fb\u30fb\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u578b\u5c3f\u9178\u30aa\u30ad\u30b7\u30c0\u30fc\u30bc\u88fd\u5264<\/p>\n\n\n\n

\u304c\u3093\u5316\u5b66\u7642\u6cd5\u306b\u4f34\u3046\u9ad8\u5c3f\u9178\u8840\u75c7\u306b\u4f7f\u7528\u304c\u8003\u616e\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u30b7\u30e7\u30c3\u30af\u306e\u5831\u544a\u306a\u3069\u304c\u3042\u308a\u4f7f\u7528\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u5f53\u9662\u3067\u306f\u51e6\u65b9\u3057\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

\n

\u53c2\u8003\u8cc7\u6599<\/p>\n\n\n\n

2019\u5e74\u6539\u8a02\u3000\u9ad8\u5c3f\u9178\u8840\u75c7\u30fb\u75db\u98a8\u306e\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3000\u7b2c\uff13\u7248\u30002022\u5e74\u8ffd\u88dc\u7248\u3000\u3000<\/p>\n<\/blockquote>\n\n\n\n

\u75db\u98a8\u767a\u4f5c\u3092\u767a\u751f\u3057\u305f\u4eba\u306e\u5c3f\u9178\u5024\u306e\u9069\u6b63\u306a\u5024\u306b\u3064\u3044\u3066<\/h2>\n\n\n\n

\u5c3f\u9178\u306e\u7d50\u6676\u3092\u7e2e\u5c0f\u3055\u305b\u308b\u306b\u306f<\/p>\n\n\n\n

\u308f\u304c\u56fd\u3067\u306f\u300e\u9ad8\u5c3f\u9178\u8840\u75c7\u30fb\u75db\u98a8\u306e\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 \u7b2c\uff13\u7248\u300f\uff082018\u5e74\uff09\u304a\u3088\u3073\u305d\u306e\u8ffd\u88dc\u7248\u304c2022\u5e74\u306b\u767a\u8868\u3055\u308c\u3001\u75db\u98a8\u306e\u6cbb\u7642\u76ee\u6a19\u306f\u3001\u5c3f\u9178\u5024\uff16mg\/dL\u4ee5\u4e0b\u3092\u76ee\u6a19\u3068\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u75db\u98a8\u7d50\u7bc0\u304c\u3042\u308b\u5834\u5408\u3082\u3001\u65e5\u672c\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\uff16mg\/dL\u4ee5\u4e0b\u3068\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3069\u306e\u7a0b\u5ea6\u306b\u30b3\u30f3\u30c8\u30ed\u2015\u30eb\u3059\u308c\u3070\u3001\u7d50\u7bc0\u306f\u7e2e\u5c0f\u3059\u308b\u306e\u304b\u3068\u3044\u3046\u70b9\u306b\u3064\u3044\u3066\u306f\u4eca\u307e\u3067\u660e\u3089\u304b\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n

\u8fd1\u5e74DECT\uff08dual-energy CT\uff09\u306b\u3088\u3063\u3066\u5c3f\u9178\u5869\u7d50\u6676\u3092\u53ef\u8996\u5316\u3067\u304d\u308b\u6642\u4ee3\u3068\u306a\u308a\u3001\u7d50\u6676\u91cf\u3092\u4f53\u7a4d\u3068\u3057\u3066\u5b9a\u91cf\u7684\u306b\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u4eca\u56de\u7d39\u4ecb\u3059\u308b\u7814\u7a76\u306f\u3001\u75db\u98a8\u60a3\u8005\u3055\u3093\u306e\u5c3f\u9178\u5869\u7d50\u6676\u6c88\u7740\u7269\uff08DECT\u3067\u8a08\u6e2c\uff09\u304c\u3001\u8840\u4e2d\u5c3f\u9178\u5024\u3092\u4e00\u5b9a\u306b\u7dad\u6301\u3057\u305f\u5834\u5408\u306b\u3001\u8840\u4e2d\u306e\u5c3f\u9178\u5024\u306e\u30ec\u30d9\u30eb\u306b\u5fdc\u3058\u3066\u3069\u306e\u3088\u3046\u306b\u7d50\u6676\u306e\u5927\u304d\u3055\u304c\uff11\u5e74\u9593\u3067\u5909\u5316\u3057\u305f\u306e\u304b\u306b\u3064\u3044\u3066\u8ffd\u8de1\u3057\u305f\u7814\u7a76\u3067\u3059\u3002<\/p>\n\n\n\n

\n

Ann Rheum Dis. 2025 Jan;84(1):136-142. doi: 10.1136\/ard-2024-226059. Epub 2025 Jan 2.<\/p>\n\n\n\n

Relationship between serum urate and changes in dual-energy CT monosodium urate crystal volume over 1 year in people with gout: an individual participant data analysis<\/p>\n\n\n\n

Brooke Kelly<\/a>, Greg D Gamble<\/a>, Anne Horne<\/a>, Anthony J Doyle<\/a>, Jill Drake<\/a>, Opetaia Aati<\/a>, Chang-Nam Son<\/a>, Ramanamma Kalluru<\/a>, Kieran Latto<\/a>, Lisa Stamp<\/a>, Nicola Dalbeth<\/a><\/p>\n<\/blockquote>\n\n\n\n

\u75db\u98a8\u60a3\u8005\u3055\u3093251\u4eba\u3001\uff13\u7814\u7a76\u306e\u7d71\u5408\u30c7\u30fc\u30bf\u3067\u89e3\u6790\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3044\u305a\u308c\u3082\u5c3f\u9178\u964d\u4e0b\u7642\u6cd5\u3092\u7528\u3044\u3066\u8840\u4e2d\u5c3f\u9178\u5024\u3092\u4e00\u5b9a\u5024\u306b\u5b89\u5b9a\u3055\u305b\u305f\u60a3\u8005\u3055\u3093\u306b\u5bfe\u3057\u3001\u4e21\u8db3\u306e\u5c3f\u9178\u7d50\u6676\u306e\u5927\u304d\u3055\u3092\u3001DECT\u691c\u67fb\u3092\u7528\u3044\u3066\u5927\u304d\u3055\u3092\u6e2c\u5b9a\u3057\u3001\uff11\u5e74\u5f8c\u306b\u3082\u6e2c\u5b9a\u3092\u884c\u3044\u3001\u7d50\u6676\u306e\u5927\u304d\u3055\u304c\u3069\u306e\u3088\u3046\u306b\u5909\u5316\u3057\u305f\u304b\u306b\u3064\u3044\u3066\u8abf\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u5e73\u5747\u8840\u6e05\u5c3f\u9178\u5024\u306e\u7bc4\u56f2\u5225\u5206\u985e\uff08\uff1c4.0\u30014.0\uff5e5\u672a\u6e80\u30015.0 \uff5e6\u672a\u6e80\u30016.0 \uff5e7\u672a\u6e80\u30017.0 \uff5e8\u672a\u6e80\u3001\u22678.0mg\/dL\uff09\u3067\u3001\u7bc4\u56f2\u5225\u306b\uff11\u5e74\u5f8c\u306e\u7d50\u6676\u4f53\u7a4d\u304c\u6709\u610f\u306b\u5897\u6e1b\u3057\u305f\u304b\u3092\u8a55\u4fa1\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u7d50\u679c<\/h2>\n\n\n\n

\u8840\u4e2d\u306e\u5c3f\u9178\u5024\u304c\uff1c\uff14.0mg\/dL\uff084.0\u672a\u6e80\uff09\u306e\u7fa4\u3067\u306f\uff0c\uff11\u5e74\u5f8c\u306bDECT\u3067\u6e2c\u5b9a\u3057\u305f\u5c3f\u9178\u5869\u7d50\u6676\u306e\u4f53\u7a4d\u304c\u6709\u610f\u306b\u6e1b\u5c11\u3057\uff0c\u660e\u3089\u304b\u306a\u7d50\u6676\u306e\u6eb6\u89e3\u304c\u89b3\u5bdf\u3055\u308c\u307e\u3057\u305f\u30024.0\uff5e5.0\u672a\u6e80mg\/dL\u306e\u7fa4\u3067\u3082\u6709\u610f\u306a\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u3001\u5c3f\u9178\u5024\u304c\uff15.0mg\/dL\u672a\u6e80\u306e\u7fa4\u3067\u306f\u6709\u610f\u306b\u7d50\u6676\u4f53\u7a4d\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u5c3f\u9178\u5024\u304c\u7d045.0\uff5e8\u672a\u6e80mg\/dL\u306e\u4e2d\u9593\u57df\u3067\u7dad\u6301\u3055\u308c\u305f\u60a3\u8005\u7fa4\u306f\u3001\uff11\u5e74\u9593\u306e\u7d50\u6676\u4f53\u7a4d\u306b\u5927\u304d\u306a\u5909\u5316\u306f\u307f\u3089\u308c\u305a\uff0c5.0\uff5e6\u672a\u6e80\u30016.0\uff5e7\u672a\u6e80\u30017.0\uff5e8\u672a\u6e80mg\/dL\u306e\u3044\u305a\u308c\u306e\u7bc4\u56f2\u3067\u3082\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u306a\u5897\u6e1b\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u307e\u305f\u3001\u5c3f\u9178\u5024\u304c\u2267\uff18mg\/dL\uff088.0\u4ee5\u4e0a\uff09\u3068\u9ad8\u5024\u304c\u6301\u7d9a\u3057\u305f\u60a3\u8005\u3067\u306f\uff0c\uff11\u5e74\u5f8c\u306b\u7d50\u6676\u4f53\u7a4d\u304c\u6709\u610f\u306b\u5897\u52a0\u3057\u3066\u304a\u308a\u3001\u65b0\u305f\u306a\u7d50\u6676\u5f62\u6210\u30fb\u6c88\u7740\u304c\u9032\u884c\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u9662\u9577\u306e\u611f\u60f3<\/h2>\n\n\n\n

\u3053\u306e\u7814\u7a76\u306f\u3001\u3069\u306e\u7a0b\u5ea6\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308c\u3070\u3044\u3044\u304b\u306b\u3064\u3044\u3066\u306e\u6839\u62e0\u3068\u3057\u3066\u610f\u5473\u306e\u3042\u308b\u7d50\u679c\u3092\u793a\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u307e\u3059\u3002\u7814\u7a76\u7d50\u679c\u304b\u3089\u306f\u3001\u5f93\u6765\u306e\u76ee\u6a19\u3067\u3042\u308b\uff16.0mg\/dL\u4ee5\u4e0b\u3067\u3082\u7d50\u6676\u3092\u5c0f\u3055\u304f\u3059\u308b\u306b\u306f\u6709\u52b9\u3067\u306f\u306a\u304f\u3001\u7e2e\u5c0f\u3055\u305b\u308b\u306b\u306f\u30015.0\u3067\u304d\u308c\u3070\uff14.0mg\/dL\u524d\u5f8c\u307e\u3067\u5c3f\u9178\u5024\u3092\u4e0b\u3052\u308b\u5fc5\u8981\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u75db\u98a8\u767a\u4f5c\u306f\u3001\u767a\u751f\u304b\u3089\u75db\u307f\u306e\u30d4\u30fc\u30af\u307e\u3067\u306e\u6642\u9593\u304c\u77ed\u304f\u3001\u75db\u307f\u306f\u6fc0\u70c8\u3067\u3059\u3002\u75db\u98a8\u767a\u4f5c\u3084\u9ad8\u5c3f\u9178\u8840\u75c7\u3067\u6cbb\u7642\u3092\u884c\u3044\u305f\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u65b9\u3092\u304a\u5f85\u3061\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u3044\u3068\u3046\u30da\u30a4\u30f3\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3001\u3042\u306a\u305f\u306e\u75db\u307f\u306b\u5fc3\u304b\u3089\u5bc4\u308a\u6dfb\u3044\u3001\u5feb\u9069\u306a\u6bce\u65e5\u3092\u53d6\u308a\u623b\u3059\u305f\u3081\u306e\u304a\u624b\u4f1d\u3044\u3092\u3055\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3059\u3002<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

\u3044\u3068\u3046\u30da\u30a4\u30f3\u30af\u30ea\u30cb\u30c3\u30af\u306e\u9662\u9577\u306e\u4f0a\u85e4\u3067\u3059\u3002\u539a\u751f\u52b4\u50cd\u7701\u304c\u6bce\u5e74\u884c\u3063\u3066\u3044\u308b\u300c\u56fd\u6c11\u751f\u6d3b\u57fa\u790e\u8abf\u67fb\u300d\u306e\u4ee4\u548c4\u5e74(2022)\u306e\u8abf\u67fb\u306b\u3088\u308b\u3068\u3001\u73fe\u5728\u3001\u75db\u98a8\u306e\u6cbb\u7642\u3067\u901a\u9662\u3057\u3066\u3044\u308b\u60a3\u8005\u7dcf…<\/p>\n","protected":false},"author":3,"featured_media":1119,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"class_list":["post-1115","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-6"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/posts\/1115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/comments?post=1115"}],"version-history":[{"count":4,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/posts\/1115\/revisions"}],"predecessor-version":[{"id":1125,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/posts\/1115\/revisions\/1125"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/media\/1119"}],"wp:attachment":[{"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/media?parent=1115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ito-pain.com\/blog\/wp-json\/wp\/v2\/categories?post=1115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}